نتایج جستجو برای: pockets
تعداد نتایج: 5069 فیلتر نتایج به سال:
BACKGROUND This study aimed to assess step-count accuracy of a piezoeletric pedometer (Yamax PW/EX-510), when worn at different body parts, and a triaxial accelerometer (GT3X+), and to compare device accuracy; and identify the preferred location(s) to wear a pedometer. METHODS Sixty-three healthy adults (45.8±20.6 years old) wore 7 pedometers (neck, lateral right and left of the waist, front ...
BACKGROUND The diagnosis of the progression of periodontitis presently depends on the use of clinical symptoms (such as attachment loss) and radiographic imaging. The aim of the multicenter study described here was to evaluate the diagnostic use of the bacterial content of subgingival plaque recovered from the deepest pockets in assessing disease progression in chronic periodontitis patients. ...
The detection and characterization of binding pockets and allosteric communication in proteins is crucial for studying biological regulation and performing drug design. Nowadays, ever-longer molecular dynamics (MD) simulations are routinely used to investigate the spatiotemporal evolution of proteins. Yet, there is no computational tool that can automatically detect all the pockets and potentia...
Complete removal of calculus is a primary part of achieving a "biologically acceptable" tooth surface in the treatment of periodontitis. Rabbani et al. reported that a single episode of scaling did not completely remove subgingival calculus and that the deeper the periodontal pocket, the less complete the calculus removal. The purpose of the present study was to evaluate the effectiveness of sc...
This research was carried out to assess Diode Laser(DL)therapeutic effects on chronic periodontitis, by reducing pockets depth and minimizing Microbial Counts (MCs). Patients(Pts)under study were 50Pts, they had chronic pockets periodontitis of more than 5mm depth, were divided into 35Pts study group(SG) and 15Pts control group(CG). All Pts were subjected to scaling, SG received DL therapy, CG ...
Thirty chronic periodontitis patients were randomly assigned to 3 groups: control, saline, and essential oil-containing antiseptic (EO). Subgingival plaque was collected from a total of 90 pockets across all subjects. Subsequently, subgingival ultrasonic instrumentation (SUI) was performed by using EO or saline as the irrigation agent. After continuous mouth rinsing at home with EO or saline fo...
CD1 proteins are unique in their ability to present lipid Ags to T cells. Human CD1b shares significant amino acid homology with mouse CD1d1, which contains an unusual putative Ag-binding groove formed by two large hydrophobic pockets, A' and F'. We investigated the function of the amino acid residues that line the A' and F' pockets of CD1b by engineering 36 alanine-substitution mutants and ana...
Protein-protein interfaces are considered difficult targets for small-molecule protein-protein interaction modulators (PPIMs ). Here, we present for the first time a computational strategy that simultaneously considers aspects of energetics and plasticity in the context of PPIM binding to a protein interface. The strategy aims at identifying the determinants of small-molecule binding, hot spots...
Functional elucidation of proteins is one of the essential tasks in biology. Function of a protein, specifically, small ligand molecules that bind to a protein, can be predicted by finding similar local surface regions in binding sites of known proteins. Here, we developed an alignment free local surface comparison method for predicting a ligand molecule which binds to a query protein. The algo...
BACKGROUND Improvements to enforce primary fixation in cemented total knee arthroplasty have been suggested to be a key issue for long-term survival. In this context, it has been questioned whether specific implant design features influence bone cement morphology and hence primary interface strength. The purpose of this study was to investigate in vitro the influence of cement pockets on the ti...
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