Phytochemicals are an important part of traditional medicine and have been investigated in detail for possible inclusion in modern medicine as well. These compounds often serve as the backbone for the synthesis of novel therapeutic agents. For many years, phytochemicals have demonstrated encouraging activity against various human cancer models in pre-clinical assays. Here, we discuss select phy...

Christine A. Williams and Jeffrey B. Harborne Botany Department, Plant Science Laboratories, University of Reading, Reading, U.K. Z. Naturforsch. 40c, 325 — 330 (1985); received February 4, 1985 Patersonia, Sisyrinchium, Sparaxis, Tigridia, Iridaceae Amentoflavone has been characterised from leaves of Patersonia glabrata. This is the first report of a biflavone in the Monocotyledoneae. The quin...

The expression levels of anoctamin 1 (ANO1, TMEM16A), a calcium-activated chloride channel (CaCC), are significantly increased in several tumors, and inhibition of ANO1 is known to reduce cell proliferation and migration. Here, we performed cell-based screening of a collection of natural products and drug-like compounds to identify inhibitors of ANO1. As a result of the screening, idebenone, mi...

The evolution of resistance by an insect to an insecticide may involve several mechanisms. Many studies have shown that insecticide-resistant insects have elevated levels of glutathione S-transferases activity in crude homogenates, which suggests a role for GSTs in resistance. This prompted us to select the GSTs from H.armigera, L.lineolaris and M.sexta due to their economic importance. The 3D ...

Includes 3 species, namely Plumbago indica P. Plumbago indica Plumbaginaceae is a perennial herb, commonly cultivated. Research project indicated that P. indica roots are indeed rich in. Nisha Sharma and Purshotam Kaushik. The present review deals with chemical compounds, medicinal.The aerial part of Plumbago indica L. family: Plumbaginaceae was studied to fix. Screening process of Plumbago ind...

The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC278...