PURPOSE In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA), Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs) and their family caregivers (FCGs), therefore addressing an important public health concern. PARTICIPANTS...

Passive leg movement (PLM), an assessment of predominantly nitric oxide-dependent vasodilation, is decreased with age and cannot be augmented by posture-induced increases in femoral perfusion pressure in older men. However, this novel method of assessing vascular function has yet to be used to evaluate alterations in nitric oxide-dependent vasodilation with age in females. PLM was performed in ...

Periodic Limb Movements (PLMs) are episodic, involuntary movements caused by fairly specific muscle contractions that occur during sleep and can be scored during nocturnal polysomnography (NPSG). Because leg movements (LM) may be accompanied by an arousal or sleep fragmentation, a high PLM index (i.e. average number of PLMs per hour) may have an effect on an individual's overall health and well...

The past years have seen growing investments in the area of product lifecycle management (PLM) by the automotive sector. Due to its complex development cycle, the automotive OEM has begun to adopt the supplier integration into its product development process. To respond to this new trend, the PLM system needs to evolve to support the collaboration and partnership management between the automoti...

In the heart, Na/K-ATPase regulates intracellular Na(+) and Ca(2+) (via NCX), thereby preventing Na(+) and Ca(2+) overload and arrhythmias. Here, we test the hypothesis that nitric oxide (NO) regulates cardiac intracellular Na(+) and Ca(2+) and investigate mechanisms and physiological consequences involved. Effects of both exogenous NO (via NO-donors) and endogenously synthesized NO (via field-...

Mathematics requires thinking but also pattern recognition. Recent research indicates that perceptual learning (PL) interventions facilitate discovery of structure and recognition of patterns in mathematical domains, as assessed by tests of mathematical competence. Here we sought direct evidence that a brief perceptual learning module (PLM) produces changes in basic information extraction. Accu...

With the deregulation of the markets and the introduction of new technologies, the need to manage diversification, change and complexity in product development has become crucial. To cope with this situation an alternative foundation for PLM is needed in which organizational issues are considered alongside with more traditional technical ones. Such a major reorientation of PLM needs to be infor...

PLM tools mainly refer information systems based on a wide graph representing linked information. Such a PLM model is compatible with a metamodel often expressed in UML. UML graphics diagrams are paradigms to support sharing and understanding the concepts and relationships that must be supported by the PLM tool. Nevertheless instance diagrams contain so many objects that it is hard to present t...

Enterprise 2.0 wird in Wissenschaft und Praxis intensiv diskutiert: In zahlreichen Fallstudien wurde analysiert, wie einzelne Plattformen in unterschiedlichen Unternehmen zum Einsatz kommen. Bisher zeichnet sich in der Enterprise-2.0-Forschung noch kein Fokus auf bestimmte Branchen oder Bereiche ab. Der vorliegende Beitrag möchte einen neuen Weg gehen, indem er nicht einzelne Plattformen und de...