To develop more green polymer composites and further know the performance of green composites, the composites based on green poly(L-lactic acid) (PLLA) and starch were fabricated by a counter-rotating mixer. And effect of starch on the fluidity and nucleating performance of PLLA was investigated using melt index instrument, optical depolarizer and wide angle X-ray diffraction instrument, respec...

BACKGROUND Poly-L-lactide materials combined with hydroxyapatite (u-HA /PLLA) have been developed to overcome the drawbacks of absorbable materials, such as radiolucency and comparably less implant strength. This study was designed to evaluate the usefulness of u-HA/PLLA material in the repair of orbital medial wall defects. METHODS This study included 10 patients with pure medial wall blow-o...

Novel poly(L-lactic acid) (PLLA)-chitosan hybrid scaffolds were developed in order to be used as tissue-engineering scaffolds and drug release carriers. The incorporation of chitosan into the PLLA porous structure allows for producing chitosan-based scaffold devices with interesting damping and stiffness aimed at being used in tissue engineering of bone or cartilage. The pore structure of the h...

A novel drug delivery system based on poly(l-lactide) (PLLA), graphite, and porphyrin was developed. In particular, 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin (THPP) was chosen because, besides its potential as codispersing agent of graphite, it is a pharmacologically active molecule. Graphite nanoplatelets, homogeneously dispersed in both the neat PLLA and the PLLA/porphyrin films, which we...

Attempts to reflect the physiology of organs is quite an intricacy during the tissue engineering process. An ideal scaffold and its surface topography can address and manipulate the cell behavior during the regeneration of targeted tissue, affecting the cell growth and differentiation significantly. Herein, silk fibroin (SF) nanoparticles were incorporated into poly(l-lactic acid) (PLLA) to pre...

Linli Zhang, Shiyun Meng, Ze Zhang Faculty of Medicine, Laval University; Saint-François d’Assise Hospital Research Center, CHUQ, Quebec, QC, Canada. Statement of Purpose: Polypyrrole (PPy) is an important intrinsically conducting polymer studied for tissue engineering and bioelectrical applications. Its composites with biodegradable polylactide (PLLA) can be used as substrate for electrically ...

In this study, the mechanical strength and modulus of poly(L-lacti acid) (PLLA) scaffolds were enhanced with the mechanical properties of boron nitride nanosheets (BNNSs) and tetraneedlelike ZnO whiskers (T-ZnOw). The adhesion and proliferation of cells were improved as well as osteogenic differentiation of stem cells was increased. Their dispersion statues in PLLA matrix were improved through ...

The stem cells in the umbilical cord stroma, or Wharton's jelly, are referred to as human umbilical cord mesenchymal stromal cells (hUCMSCs) and have been shown to differentiate along a chondrogenic lineage. The aim of this study was to evaluate the chondrogenic differentiation of hUCMSCs in either polyglycolic acid (PGA) or poly-L-lactic acid (PLLA) non-woven mesh scaffolds for cartilage tissu...

In this study, the macroporous poly(L-lactide) (PLLA) cell scaffold was modified for enhancing its cell affinity by an improved surface-treating medium, a mixture of aqueous 0.25 M NaOH/ethanol. Ethanol was applied as a co-treating medium to wet the polylactone and assist the hydroxide nucleophilic attack on the ester bond. Low concentration of NaOH could be applied, severe bulk degradation cou...

Poly-L-lactic acid (PLLA) is a synthetic injectable medical agent used to treat patients with loss of volume in the face, chest, and hands. It consists of a biodegradable and bioresorbable powder, a synthetic nonpermanent polymer. PLLA was introduced in Europe in 1999 (NewFill; Ashford Aesthetics Inc., Brussels, Belgium) under the category of wrinkle filler [1]. The Food and Drug Administration...