The frequency of adherent placenta is increasing due to growing number of caesarean deliveries. The optimal management of this condition remains unclear, resulting in complications in the peripartum period such as severe haemorrhage, a possible need for caesarean hysterectomy, and even severe injuries to pelvic organs. We report cases of conservative management of adherent retained placenta fol...

We investigated the in vitro transfer of three parathyroid hormone (PTH) fragments (amino acids 35-84, 44-68 and 65-84) through human placenta at term. The perfused and transferred fragments were measured radioimmunologically and identified by three different methods: high-pressure-liquid chromatography (HPLC), preparative flat-bed electrofocusing (PEGG), and gel filtration (GF). The study demo...

Mesenchymal stem cells (MSC) are being used increasingly in clinical trials for a range of regenerative and inflammatory diseases. Bone marrow is the traditional source but is relatively inaccessible in large volume. MSC have now been derived from tissues other than bone marrow including placenta and adipose tissue. We have used placenta obtained after delivery as a source of MSC and have been ...

Purpose: Placenta previa and morbidly adherent placenta are life-threatening conditions that necessitate close monitoring during pregnancy can result in increased ante- intrapartum complications. This study aims to evaluate the frequency of placental disorders our population, reveal impact known risk factors on maternal morbidity, new predisposing their effects outcomes. Materials Methods: We p...

Human papillomavirus (HPV) is suggested to infect trophoblasts in the placenta, and HPV infections are reported to be more prevalent in pregnancies with adverse outcomes. Results are however controversial, and studies investigating the molecular consequences of placental HPV infections are lacking. We studied HPV DNA localization in the placenta in cases of spontaneous abortion/spontaneous pret...

Objectives: To determine whether staged procedure involving classical Caesarean section without removing the placenta followed by arterial embolisation before hysterectomy had any clinical value in the surgical management of placenta accreta. Methods: This retrospective case-controlled study was conducted in a tertiary obstetric unit in Hong Kong. All hysterectomy cases with confirmed histologi...

Introduction: Placenta accreta occurs when part of the placenta or the entire placenta invades and is inseparable from the uterine wall. The diagnosis of placenta accreta before delivery allows multidisciplinary planning in an attempt to minimize potential maternal or neonatal morbidity and mortality. The diagnosis is usually established by ultrasonography and occasionally supplemented by magne...

Dual perfusion of the isolated lobule of the human placenta is increasingly used for transport and metabolic studies: the method is relatively simple because only a portion of the large organ is used [24]. Assessment of the biological function of the^preparation is most important for the trophqblast is known to have a high oxygen consumption [6] a high glucose utilization rate [23] and a high p...

OBJECTIVE Placenta increta or percreta is an uncommon pathology, sometimes associated with high maternal morbidity. Its prevalence increases proportionally to the number of cesarean sections. This study analyzed the changes of our management strategy to devise treatment guidelines for this uncommon disorder. MATERIALS AND METHODOLOGY Between 2005 and 2011, 10 cases of placenta increta or perc...