Ibuprofen (I) is the most widely used non-steroidal anti-inflammatory drugs (NSAIDs) has been synthesized in recent years. NSAIDs are the first choice of drugs that are normally used for the treatment of pain and inflammation. There are many methods for synthesizing of I but each one has some difficulties as raw materials preparation, reaction conditions and etc. In an effort to establish modif...

lactide was synthesized by reverse polymerization of low molecular weight poly(lactic acid) with two different molecular weights:1500 and 2500. two different lactide purification processes such as: recrystallization in ethyl acetate and washing the crude lactide with ether before recrystallization in ethyl acetate were evaluated. it has been demonstrated that increasing the molecular weight of ...

In the present study, the antioxidant potential of the crude methanol and its fractionated extracts (hexane, ethyl acetate and water) of the rhizomes of Alpinia mutica was investigated, employing four different assays. The antioxidant assays used were 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, β-carotene bleaching, superoxide dismutase (SOD) and the reducing power assays while th...

The ethyl, ethyl N-hydroxy, isopropyl, and methyl esters of carbamic acid were examined for their abilities to induce sister chromatid exchanges (SCEs) in alveolar macrophages, bone marrow, and regenerating liver cells of C57BL/6J X DBA/2J F1 mice. The relative potencies in inducing SCE, ethyl greater than ethyl N-hydroxy- greater than isopropyl, paralleled previously described activities for i...

Stability and interface properties of cellulose acetate propionate (CAP) and cellulose acetate butyrate (CAB) films adsorbed from acetone or ethyl acetate onto Si wafers have been investigated by means of contact angle measurements and atomic force microscopy (AFM). Surface energy (gamma(S)(total)) values determined for CAP adsorbed from acetone are larger than those from ethyl acetate. In the ...

Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent. In this study, we investigated the effect of ethyl linoleate on the melanogenesis and the mechanism underlying its action on melanogenesis in B16F10 murine melanoma cells. Our results reve...

The resinous wood of Aquilaria sinensis, known as agarwood (Chen Xiang in Chinese), is traditionally used for the treatment of abdominal pain, vomiting, circulatory disorders, and dyspnea. Four new 2-(2-phenylethyl)-4H-chromen-4-one derivatives, namely 7-methoxy-2-[2-(4'-hydroxy-phenyl)ethyl]chromone (1), 7-hydroxy-2-[2-(4'-methoxyphenyl)ethyl]chromone (2), 5,6-dihydroxy- 2-[2-(3'-hydroxy-4'-me...

Icosapent ethyl is a high-purity prescription form of eicosapentaenoic acid (EPA) ethyl ester approved at a dose of 4g/day as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500mg/dL) hypertriglyceridemia. This post-hoc exploratory analysis examined the relationship of icosapent ethyl dose with EPA concentrations in plasma and red blood cells (RBCs) across ...