OBJECTIVE Maternal immune activation (MIA) triggered by infections has been identified as a cause of autism in offspring. Considering the involvement of perturbations in innate immunity in epilepsy, we examined whether MIA represents a risk factor for epilepsy as well. The role of specific MIA components interleukin (IL)-6 and IL-1β was also addressed. METHODS MIA was induced in C57BL/6 mice ...

A comparison was made of Al2O3 films deposited on Si via prompt inorganic condensation (PIC) and atomic layer deposition (ALD). Current–voltage measurements as a function of annealing temperature indicate that the solution-processed PIC films, annealed at 500 C, exhibit lower leakage and roughly equivalent breakdown strength in comparison to ALD films. PIC films are less dense than as-deposited...

Micro-TPC, a time projection chamber (TPC) with micro pixel chamber (μ-PIC) readout was developed for the detection of the three-dimensional fine (∼ sub-millimeter) tracks of charged particles. We developed a two-dimensional position sensitive gaseous detector, or the μ-PIC, with the detection area of 10 × 10 cm and 65536 anode electrodes of 400 μm pitch. We achieved the gas gain of more than 1...

Here, we describe novel polyion complex (PIC) particles for the delivery of Polymyxin B (Pol-B), an antimicrobial peptide currently used in the clinic as a last resort antibiotic against multidrug-resistant gram-negative bacteria. A range of conditions for the controlled assembly of Pol-B with poly(styrene sulphonate) (PSS) has been identified which let us prepare stable colloidal PIC particles...

Microcontrollers are very popular in electronics and computer-controlled systems worldwide. This paper presents the control of a microcontroller-based system using the computer and explains comprehensively the hardware and software parts of the microcontroller. Peripheral Interface Controller (PIC) software developed by Microchip (MPASM) is used in programming a PIC microcontroller, and Visual ...

Space-time parallel interference cancellation (ST-PIC) is an effective multi-stage multiuser detection scheme for wideband code-division multiple access (W-CDMA). However, the realization of ST-PIC requires accurate channel estimate, a sufficient number of stages, and knowledge of all user’s spreading waveforms. With inaccurate channel estimate or insufficient number of stages, the residual mul...

Parallel interference cancellation (PIC) principle is conceptually simple and yet eeective method of parameter estimation and data detection in the presence of multiple-access and multipath interference. It uniies some of the known methods of data detection, complex channel co-eecient estimation, as well as delay tracking in DS-CDMA receivers. The PIC method will be derived and some numerical r...

Transcription by all three eukaryotic RNA polymerases involves the assembly of a large preinitiation complex (PIC) at gene promoters. The PIC comprises several general transcription factors (GTFs), including TBP, and the respective RNA polymerase. It has been suggested that some GTFs remain stably bound at active promoters to facilitate multiple transcription events. Here we used two complement...

The current paradigm of cosmic ray (CR) origin states that the most part galactic CRs is produced by supernova remnants. interaction ejecta with interstellar medium after supernova's explosions results in shocks responsible for CR acceleration via diffusive shock (DSA). We use particle-in-cell (PIC) simulations and a combined PIC-magnetohydrodynamic (PIC-MHD) technique to investigate whether DS...

The aim of this thesis is to investigate practical multiuser demodulation algorithms for mobile communications systems that are based on code division multiple access ( C D M A ) technologies. These include the adaptive receiver and the interference canceller. The overall complexity of implementing them is examined. The effects of the proposed algorithms on reducing of multiple access interfere...