BACKGROUND Ultraviolet (UV) light exposure has been one of the major inducers of apoptosis. UV exposure has caused pyrimidine dimers and DNA fragmentation which might lead to cell cycle arrest and apoptosis signals activation. UV induced apoptosis has investigated in MDA-MB 468 as an ER negative breast adenocarcinoma and MCF-7 as an ER positive breast cancer cell line. Apoptosis induction rate ...

Apoptotic cells in animals are engulfed by phagocytic cells and subsequently degraded inside phagosomes. To study the mechanisms controlling the degradation of apoptotic cells, we developed time-lapse imaging protocols in developing Caenorhabditis elegans embryos and established the temporal order of multiple events during engulfment and phagosome maturation. These include sequential enrichment...

Microglial cells have been attributed both neuroprotective and neurodegenerative roles in cerebral ischemia. This study presents an immunotoxic method for depletion of microglia from mouse hippocampal slice cultures and the effect of this on ischemia-like oxygen-glucose deprivation (OGD). For microglial depletion hippocampal slice cultures were exposed for 7 days to saporin coupled to an antibo...

Little is known about whether the depth of vestibular fornix influences people’s ability to access their teeth remove plaque during oral hygiene measures at home. This study aimed investigate association between and periodontal health. The included 100 adults in good health, with a index (PI) ≤15%, bleeding on probing (BOP) ≤10%, pocket (PPD) ≤3 mm. Using probe digital caliper, we measured PI, ...

Bounds are derived for rotating Rayleigh–Bénard convection with free slip boundaries as a function of the Rayleigh, Taylor and Prandtl numbers ${\textit {Ra}}$ , {Ta}}$ {Pr}}$ . At infinite {Ta}} > 130$ Nusselt number {Nu}}$ obeys {Nu}} \leqslant \frac {7}{36} \left ({4}/{{\rm \pi} ^2} \right )^{1/3} {\textit {Ra}} {Ta}}^{-1/3}$ whereas kinetic energy density $E_{kin}$ $E_{kin} ({7}/{72 {\rm...

Submitted by drupal on Thu, 10/23/2014 13:51 Firm: Applied Research, LLC [2] Award Solicitation: NASA SBIR 2014 Phase I Solicitation [3] Award ID: SBIR_14_P1_144710 Award Topic: Algorithms and Tools for Science Data Processing, Discovery and Analysis, in State-of-the-Art Data Environments [4] Award Dollars: 124 999.00 Award Lead Center: Goddard Space Flight Center [5] Proposal Number: S5.03-929...

Submitted by drupal on Wed, 10/23/2013 18:04 Firm: ADVR, Inc. [2] Award Solicitation: NASA STTR 2010 Phase I Solicitation [3] Award ID: STTR_10_P1_100163 Award Topic: Lidar, Radar, and Passive Microwave [4] Award Dollars: 99 984.00 Award Lead Center: Goddard Space Flight Center [5] Proposal Number: T4.01-9837 Proposal Title: A Waveguide Based, High Power Pockels Cell Modulator for Sub-Nanosecon...

Submitted by drupal on Fri, 03/04/2016 16:48 Firm: Microelectronics Research Development Corporation [2] Award Solicitation: NASA SBIR Select 2014 Phase II Solicitation [3] Award ID: SBIR_14_P2_S_144053 Award Topic: Radiation Hardened Application Specific Integrated Circuit (ASIC) Platforms [4] Award Dollars: 1 499 950.00 Award Lead Center: Goddard Space Flight Center [5] Proposal Number: S20.0...