Analyzing physiological data can be of great importance in unearthing information on the course of a disease. In this paper we propose a data mining approach to analyze these data and acquire knowledge, in the form of temporal patterns, on the physiological events which can frequently trigger particular stages of disease. The application to the sleep sickness scenario is addressed to discover p...

Six patients with the physiological features of the myasthenic syndrome associated with carcinoma are presented. The clinical features encountered in this group, including age, mode of onset, and duration of symptom indicate that it may escape detection owing to its resemblance to other neuromuscular disorders. Conventional concentric needle electromyography may lead to the disorder being confu...

A number of illnesses and other factors can affect the function of the neuromuscular junction (NMJ). These may have an affect at pre- or post-junctional sites. This review outlines the anatomy and the physiology of the NMJ. It also describes the mechanisms and physiological basis of many of the disorders of the NMJ. Finally, the importance of these disorders in anaesthetic practice is discussed.

Computational models are useful tools for exploring the nature of human cognitive processes. In particular, connectionist models are providing researchers with new ways of thinking about the basic nature of cognition and its implementation in the brain. They support novel explanations of important aspects of perception, memory, language, thought and cognitive development, and allow cognitive pr...

introduction: neurons in layer ii and iii of the somatosensory cortex in rats show high frequency (33 ± 13 hz) of miniature excitatory postsynaptic currents (mepscs) that their rates and amplitudes are independent of sodium channels. there are some changes in these currents in neurodegenerative and psychological disorders. regarding to well known roles of the neuromodulatory brain systems in th...

The effects of shift work on physiological function through disruption of circadian rhythms are well described. However, shift work can also be associated with specific pathological disorders. This article reviews the evidence for a relationship between specific medical disorders and working at night or on shift systems. The strongest evidence exists for an association with peptic ulcer disease...

Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.

Obesity and its associated disorders are a growing epidemic across the world. Many genetic, physiological, and behavioral factors play a role in the etiology of obesity. Diet and exercise are known to play a valuable role in the treatment and prevention of obesity and associated disorders such as hypertension, heart disease, and diabetes. Therefore, the purpose of this review is to examine the ...

Online learning activities carried out by students spend several hours a day in front of computers and smartphones. If the this are not aligned with ergonomic approach each student's activity, course, it will cause subjective fatigue experienced students. This study aims to determine influence implementation on sociology decrease physiological disorders assessed from high school students, espec...

Objectives To characterize the most common peripheral and central neurological disorders during pregnancy. Methods Original research and review of the literature on neurological complications during pregnancy. We searched for keywords related to the topic on different databases. Results Pregnancy involves physiological changes that can trigger peripheral neurological and/or central nervous syst...