OBJECTIVES The role of occupational exposures in hairy cell leukaemia was investigated through a multicentre, hospital based, case-control study. This paper analyses the role of exposure to solvents other than benzene in hairy cell leukaemia. METHODS The study included 226 male cases and 425 matched controls, exposure to solvents was evaluated by expert case by case review of the detailed dat...

An amphiphilic electron-deficient (n-type) perylene diimide has been synthesized and characterized. The diimide contains a hydrophobic long chain on one end and a hydrophilic ethoxy chain on the other. The self-assembly of this molecule in polar and nonpolar solvents has been demonstrated by concentration- and temperature-dependent absorption and fluorescence spectroscopies. Analysis of the spe...

The global bio-based chemical market is growing in size and importance. Bio-based solvents such as glycerol and 2-methyltetrahydrofuran are often discussed as important introductions to the conventional repertoire of solvents. However adoption of new innovations by industry is typically slow. Therefore it might be anticipated that neoteric solvent systems (e.g., ionic liquids) will remain niche...

The photostability of aromatic compounds in the presence of air is significantly improved through perfluoroalkylation of the corresponding aromatic cores and use of polyfluorinated solvents despite higher O(2) concentration in polyfluorinated solvents than in hydrocarbon solvents.

A recently developed density functional theory (DFT) for tethered bead-spring chains is used to investigate colloidal forces for the good solvent case. A planar surface of tethered chains is opposed to a bare, hard wall and the force exerted on the bare wall is calculated by way of the contact density. Previously, the case of large wall separation was investigated. The density profiles of the u...

Analysis of Raman and neutron scattering spectra of lysozyme demonstrates that the protein dynamics follow the dynamics of the solvents glycerol and trehalose over the entire temperature range measured 100-350 K. The protein's fast conformational fluctuations and low-frequency vibrations and their temperature variations are very sensitive to behavior of the solvents. Our results give insight in...

A complete description of the Supercritical Antisolvent Process requires the modelling of several complex physical phenomena such as heat and mass transfer, hydrodynamic, phase equilibria of ternary mixtures, and nucleation /growth of the specie to be precipitated; moreover, the description should also account for the biphasic case, where the jet of organic solvent breaks up as droplets. As a f...

At present, physical chemistry employs the tools of thermodynamics to treat osmosis across a semipermeable membrane. We propose a model in terms of momentum transfer, the inherent asymmetry of which leads quantitatively to the van't Hoff relationship; qualitatively, the solute molecules can be looked upon as micropumps that suck solvent through the pores in the membrane.

Poisson-Boltzmann (PB) theory is the classic approach to soft matter electrostatics and has been applied to numerous physical chemistry and biophysics problems. Its essential limitations are in its neglect of correlation effects and fluid structure. Recently, several theoretical insights have allowed the formulation of approaches that go beyond PB theory in a systematic way. In this topical rev...

We study theoretically the phoretic motion of a spheroidal particle, which generates solute gradients in the surrounding unbounded solvent via chemical reactions active on its surface in a cap-like region centered at one of the poles of the particle. We derive, within the constraints of the mapping to classical diffusio-phoresis, an analytical expression for the phoretic velocity of such an obj...