PURPOSE To compare the effect of Homatropine and Diclofenac eye drops for reducing pain after photorefractive keratectomy (PRK). METHODS This randomized, double-masked, interventional study included 32 patients (64 eyes) who underwent bilateral PRK. After operation, patients received Homatropine eye drops in one eye and Diclofenac eye drops in the fellow eye for 48 h. The level of pain was ev...

Purpose. To assess refractive and visual outcomes and patient satisfaction of wavefront-guided photorefractive keratectomy (PRK) in eyes with myopia and compound myopic astigmatism, with the ablation profile derived from a new Hartmann-Shack aberrometer. Methods. In this retrospective study, 662 eyes that underwent wavefront-guided PRK with a treatment profile derived from a new generation Hart...

OBJECTIVE To evaluate the results of photorefractive keratectomy (PRK) with mitomycin C in myopia correction after five years. METHODS This is a cross sectional study which included 145 eyes of 74 patients in 18 to 51 years age group that were undergoing Photorefractive keratectomy with mitomycin C using Allegretto Wave Eye-Q 400-Hz excimer laser platform in Markazi Eye Center, Tehran, Iran. ...

PURPOSE The analgesic efficacy and safety of topical ketorolac tromethamine 0.5% ophthalmic solution (Acular) in photorefractive keratectomy was compared to its vehicle. METHODS Double-masked, multicenter, study of 200 patients dosed with 1 drop of study medication (ketorolac or vehicle) in the operated eye immediately after surgery (eye patched), with four-times daily dosing for the next 3 d...

PURPOSE To determine whether the nerve fiber analyzer GDx with the new variable corneal compensation (VCC) device allows measurements of retinal nerve fiber layer parameters independent from birefringence changes of the cornea after photorefractive keratectomy (PRK). METHODS Retinal nerve fiber layers of 32 eyes in 32 myopic patients undergoing PRK were analyzed using the GDx-VCC. Photorefrac...

PURPOSE To use a double-pass system to compare the optical quality after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for mild to moderate myopia. SETTING Universitat Politècnica de Catalunya, Terrassa, Barcelona Institute of Ocular Microsurgery, Barcelona, Spain. DESIGN Comparative case series. METHODS Optical quality was assessed with a clinical double-pass...

PURPOSE To evaluate possible changes of the ocular rigidity coefficient in vivo after photorefractive keratectomy (PRK) in a series of rabbit eyes, using an invasive ocular rigidity measurement device. METHODS Sixteen eyes of 8 rabbits were used in this study. One eye from each rabbit underwent PRK for -10.00 diopters (D) in a 5-mm optical zone (92 microm) while the fellow eye served as the c...

BACKGROUND/AIMS The Fas-Fas ligand system is thought to be involved in stromal cell apoptosis after corneal wounding. The aim was to measure changes in human tear fluid levels of soluble Fas (sFas) and Fas ligand (sFasL) following myopic photorefractive keratectomy (PRK). METHODS Tear samples of 59 patients were collected preoperatively, and 1 or 2 days after PRK. Tear fluid sFas or sFasL con...