The in vivo and ex vivo distributions and the pharmacological profile of the fluorinated phenylpiperazine derivative p-[(18)F]MPPF (4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)-p-fluorobenzamido]-et hyl piperazine) were evaluated in the cat brain as a potential selective antagonist for 5-HT(1A) receptors using PET. After intravenous injection of p-[(18)F]MPPF in cats, there was a rapid accumulat...

The Diagnostic and Statistical Manual of Mental Disorders (DSM–IV–TR) currently conceptualizes personality disorders (PDs) as categorical syndromes that are distinct from normal personality. However, an alternative dimensional viewpoint is that PDs are maladaptive expressions of general personality traits. The dimensional perspective postulates that personality pathology exists at a more extrem...

We report the synthesis of small (below 100 nm), stable and water-compatible superparamagnetic molecularly imprinted nanocomposites using water-soluble, dithiocarbamate-based photoiniferters. These agents were adsorbed directly on surface maghemite nanoparticles allowed thin layers polymer able to specifically selectively bind green fluorescent protein as a model protein. To best or our knowled...

Selenium deficiency in daily diet is a common problem many countries, thus searching for new dietary sources of this trace element an important scientific challenge. biofortified sprouts from Brassicaceae family are good candidates selenium source, as they reveal one the highest capability to synthesize and accumulate element. As part extensive search, influence novel organic compounds on forti...

In the personality disorder section of the DSM-V research agenda, the authors stress the need for studies on the relevance of a change from diagnostic categorical models to dimensional ones. These studies should identify the underlying genetic and neurobiologic mechanisms and appropriate representation on the dimensions of clinical criteria as cognitive disturbances, identity conflicts and atta...

Olive knot disease, caused by the bacterium Pseudomonas savastanoi pv. savastanoi, seriously affects olive trees in the Mediterranean basin. Here, we report the draft genome sequence of P. savastanoi pv. savastanoi DAPP-PG 722, a strain isolated in Italy from an olive plant affected by knot disease.