The increasing resistance of Campylobacter to clinically important antibiotics, such as fluoroquinolones and macrolides, is a serious public health problem. The objective of this study is to investigate synergistic anti-Campylobacter jejuni activity of fluoroquinolones and macrolides in combination with phenolic compounds. Synergistic antimicrobial activity was measured by performing a checkerb...

A recent study showed that N-acylserotonin derivatives have strong inhibitory activity against tyrosinase. To clarify the role of the 5-hydroxy group in the indole ring, 2-, 4-, 5-, 6-, and 7-hydroxyindole and 11 related compounds such as 5-hydroxyindan and 6-hydroxyquinoline were tested for their inhibition of catecholase activity of tyrosinase from human HMV-II melanoma cells. 6-Hydroxyindole...

the effect of postharvest uv-c irradiation on phenolic compounds accumulation was investigated in berries of ‘rishbaba’ table grape (vitis vinifera cv. rishbaba). grape clusters were harvested at mature stage and irradiated with uv-c using fluorescent germicidal lamp (30 w, 90 cm) with a peak emission at 254 nm for 0 (control), 5 and 10 min. uv-c treatment had significant effect on individual p...

in this study, the antioxidant activity and protective effects of purslane seed water-methanolic extract (pswme) in stabilizing soybean oil (sbo) were tested. dpph radical scavenging activity of pswme at different concentrations varied significantly (p< 0.05), ranging from 15.41% to 79.06%. total phenolic content in pswme was 121.09 mg gallic acid equivalent (gae) kg-1 dw. the protective effect...

wheat streak mosaic virus (wsmv) causes extensive economic damage to wheat (triticum aestivum l.) in many regions of the world. the present study was conducted to find out if the variations in biochemical changes in reaction to wsmv infection in f2 generation of either potentially resistant (adl-cross) or susceptible (marvdasht) cultivars are genetically inherited. a factorial experiment was em...

nowadays, the use of natural antioxidants as alternative antioxidants is more acceptable than synthetic antioxidants mainly for negative effects such as carcinogenicity and toxicity. this has led to an increasing interest in the search for natural antioxidants. the objectives of this study were to measure total crude phenolic compounds and in sorghum grain as natural antioxidant sources, to det...

Protein aggregation with the concomitant formation of amyloid fibrils is related to several neurodegenerative diseases, but also to non-neuropathic amyloidogenic diseases and non-neurophatic systemic amyloidosis. Lysozyme is the protein involved in the latter, and it is widely used as a model system to study the mechanisms underlying fibril formation and its inhibition. Several phenolic compoun...

Gypsophila paniculata is an ornamental crop with medicinal value. To date, limited information has been reported about the natural products in G. to explain its function. The current study reports found stem for first time. Thirty-three compounds were isolated from extract of and identified by gas chromatography-mass spectrometry, 10 which have contents &gt;2%. These 2-O-methyl-D-mannopyranose ...

Isolation of compounds from the root of Rhodiola sachalinensis (RRS) yielded tyrosol (1), salidroside (2), multiflorin B (3), kaempferol-3,4'-di-O-β-D-glucopyranoside (4), afzelin (5), kaempferol (6), rhodionin (7), and rhodiosin (8). Quantification of these compounds was performed by high-performance liquid chromatography (HPLC). To investigate the antioxidant and anti-inflammatory effects of ...

Allergic diseases such as atopic dermatitis, rhinitis, asthma, and anaphylaxis are attractive research areas. Tyrosol (2-(4-hydroxyphenyl)ethanol) is a polyphenolic compound with diverse biological activities. In this study, we investigated whether tyrosol has anti-allergic inflammatory effects. Ovalbumin-induced active systemic anaphylaxis and immunoglobulin E-mediated passive cutaneous anaphy...