نتایج جستجو برای: phenanthridine
تعداد نتایج: 222 فیلتر نتایج به سال:
Chelerythrine (CHE), a natural benzo[c]phenanthridine alkaloid, shows anti-cancer effect through a number of mechanisms. Herein, the effect and mechanism of the CHE-induced autophagy, a type II programmed cell death, in non-small cell lung cancer (NSCLC) cells were studied for the first time. CHE induced cell viability decrease, colony formation inhibition, and apoptosis in a concentration-depe...
Lycorine, a main phenanthridine Amaryllidaceae alkaloid, has shown wide ranging pharmacological activities. This study aimed to investigate the antitumor activity of lycorine against pancreatic cancer and to elucidate the underlying mechanisms. Human pancreatic cancer cell line PANC-1 was treated with lycorine. Cell viability was monitored by MTT assay. The expression of related proteins was id...
Group 8 complexes of π-extended N-heterocyclic ligands present some unexpected results. Benzannulation shifts the lowest energy excitation to blue by impacting character transition rather than affecting frontier orbital energies.
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