Traditionally, the contractile properties of airway smooth muscle have been regarded as its sole contribution to the pathogenesis of asthma. However, our understanding of the role that this structural cell plays in asthma is changing. Airway smooth muscle can undergo hyperplasia and/or hypertrophy leading to structural changes in the airway wall which contribute to the development of persistent...

OBJECTIVE To investigate whether airway granulation, a common occurrence during laryngotracheal reconstructive surgery and a common cause of delays in definitive treatment and treatment failure, is associated with a microbial etiology. DESIGN Prospective case-control study. SETTING Tertiary referral airway reconstruction unit. PATIENTS Patients who had an airway stent as part of their tre...

While airways have some degree of baseline tone, the level and variability of this tone is not known. It is also unclear whether there is a difference in airway tone or in the variability of airway tone between asthmatic and healthy individuals. This study examined airway tone and intraindividual airway tone heterogeneity (variance of airway tone) in vivo in 19 individuals with asthma compared ...

BACKGROUND Airway hyperresponsiveness is the ability of airways to narrow excessively in response to inhaled stimuli and is a key feature of asthma. Airway inflammation and ventilation heterogeneity have been separately shown to be associated with airway hyperresponsiveness. A study was undertaken to establish whether ventilation heterogeneity is associated with airway hyperresponsiveness indep...

Introduction: Fibroepithelial polyp (FEP) is a benign tumor that presented frequently in some of the organs like oral cavity, skin, colon and genitourinary tract, but airway rare. Case Presentation: We present rare case this paper, with recurrent bronchial FEP was near completely obstructed right main bronchus we managed her successfully interventional bronchoscopy. In report describe condition...

The anaesthetic management of paediatric patients with Patau syndrome presents unique challenges, particularly when combined craniofacial and cardiac defects limited airway resources. This case report highlights our experience in managing a syndromic child difficult resource-constrained environment. inability to secure the adequately can pose significant perioperative risks. In this case, we su...