نتایج جستجو برای: pestivirus

تعداد نتایج: 499  

Journal: :Proceedings 2020

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Journal: :Frontiers in Microbiology 2016

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2015
Fun-In Wang Ming-Chung Deng Yu-Liang Huang Chia-Yi Chang Andrew Ward

Pestiviruses, which include economically important animal pathogens such as bovine viral diarrhea virus and classical swine fever virus, possess three envelope glycoproteins, namely Erns, E1, and E2. This article discusses the structures and functions of these glycoproteins and their effects on viral pathogenicity in cells in culture and in animal hosts. E2 is the most important structural prot...

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Journal: :Journal of virology 1996
N Tautz G Meyers R Stark E J Dubovi H J Thiel

Cytopathogenic (cp) bovine viral diarrhea virus (BVDV) strains are generated in cattle persistently infected with noncytopathogenic (noncp) BVDV.cp BVDV strains are considered crucial for the development of fatal mucosal disease. Comparative analysis of cp and noncp BVDV strains isolated from one animal suffering from mucosal disease revealed that the genomes of the cp BVDV strain (CP7) and the...

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Journal: :Nucleic Acids Research 2020

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Journal: :Polish Journal of Veterinary Sciences 2023

A disease survey was conducted between 2014 and 2018 in the Polish goat population to determine seroprevalence of pestiviral infection. Blood samples from 910 goats (782 females 128 males) were collected 62 herds tested for bovine viral diarrhea virus (BVDV) infection with a competitive ELISA serial fashion. Between 10 13 adult female randomly selected each herd, assuming individual-level herd ...

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Journal: :Proceedings of the National Academy of Sciences of the United States of America 2000
S G Baginski D C Pevear M Seipel S C Sun C A Benetatos S K Chunduru C M Rice M S Collett

We report here the discovery of a small molecule inhibitor of pestivirus replication. The compound, designated VP32947, inhibits the replication of bovine viral diarrhea virus (BVDV) in cell culture at a 50% inhibitory concentration of approximately 20 nM. VP32947 inhibits both cytopathic and noncytopathic pestiviruses, including isolates of BVDV-1, BVDV-2, border disease virus, and classical s...

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Journal: :Developmental Medicine & Child Neurology 2006

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Journal: :Veterinary Microbiology 2011

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Journal: :The Journal of general virology 2007
Thomas Bruun Rasmussen Ase Uttenthal Ilona Reimann Jens Nielsen Klaus Depner Martin Beer

A chimeric pestivirus of border disease virus Gifhorn and bovine viral diarrhea virus CP7 (Meyers et al., 1996) was constructed. Virulence, immunogenicity and vaccine properties of the chimeric virus were studied in a vaccination-challenge experiment in pigs. The chimeric virus proved to be avirulent and neither chimeric virus nor viral RNA was detected in serum after vaccination. The safety of...

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