نتایج جستجو برای: personalised medicine
تعداد نتایج: 255238 فیلتر نتایج به سال:
The 2014 OECI Oncology Days was held at the 'Prof. Dr. Ion Chiricuta' Oncology Institute in Cluj, Romania, from 12 to 13 June. The focus of this year's gathering was on developments in personalised medicine and other treatment advances which have made the cost of cancer care too high for many regions throughout Europe.
At the Systems Biology Lab of the University of Florida, we are developing an integrated system, PHW service, for accessing and storing and monitoring information in personalised medicine. We intend to take a practical approach to build such a system in the framework of clinical and translational sciences of the NIH Roadmap.
Hypertension, defined as a systolic/diastolic blood pressure of 140/90 mmHg or greater, is estimated to carry a three-fold increased risk of developing cardiovascular diseases (CVDs). Evidence from genome-wide association studies has identified an association between blood pressure and the gene encoding the folate-metabolising enzyme, methylenetetrahydrofolate reductase (MTHFR). Recent meta-ana...
Asthma and chronic obstructive pulmonary disease (COPD) are prevalent conditions, and despite recent advances and multiple available therapies and interventions, there remains a significant unmet clinical need. In recent years, it has become clear that there is both significant heterogeneity within each of these conditions and additionally significant overlap in many of the clinical and inflamm...
The studies presented here were carried out at: Bloed gebaseerde biomarkers voor personalised medicine applicaties in schizofrenie Thesis to obtain the degree of Doctor from the Erasmus University Rotterdam by command of the Rector Magnificus INTRODUCTION Parts of the present chapter were published in: " Blood test for schizophrenia ". " Proteomic profiling in schizophrenia: enabling stratifica...
The creation and use of biobanks is an actively growing field that plays important role in the development many branches biotechnology biomedicine, including oncology translational medicine. In this review, based on analysis more than 80 Russian foreign publications, we describe current state biobanking its future perspectives. diversity problems arising from it, limits applicability to differe...
THE RIGHT TREATMENT, FOR THE RIGHT PATIENT, AT THE RIGHT TIME The concept of personalised or stratified therapies is not a new one. For centuries, physicians have observed that the manifestation of a disease and its response to intervention can vary according to many factors including age, sex, ethnicity, diet and the type of administered drug [1]. Hippocrates, for example, observed over 2,000 ...
BACKGROUND Chronic myeloid leukaemia (CML) is characterised by the presence of a fusion driver oncogene, BCR-ABL1, which is a constitutive tyrosine kinase. Tyrosine kinase inhibitors (TKIs) are the central treatment strategy for CML patients and have significantly improved survival rates, but the T315I mutation in the kinase domain of BCR-ABL1 confers resistance to all clinically approved TKIs,...
BACKGROUND Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease whose assessment and management have traditionally been based on the severity of airflow limitation (forced expiratory volume in 1 s (FEV1)). Yet, it is now clear that FEV1 alone cannot describe the complexity of the disease. In fact, the recently released Global Initiative for Chronic Obstructive Lung Disease (G...
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