INTRODUCTION Early diagnosis and treatment of Kawasaki disease as the most common cause of acquired heart disease in childhood, may significantly improve the prognosis. Diagnosing infantile Kawasaki (younger than a year) is difficult because of obscure symptoms; at the same time they are at the higher risk of coronary abnormalities. CASE PRESENTATION We report three infants with prolonged (mo...

The administration of ergot or ergot derivatives has been shown to result in a continuous spasm of the muscular coat of peripheral arteries, leading to cyanotic induration, ulceration, and, in many instances, to gangrene of the tissues.1' 25,7 In 1935, McGrath reported4 that female albino rats could be protected from the more severe manifestations of ergotamine intoxication by the daily injecti...

More and more cases of H1N1 influenza are being detected in India and so also the variety of complications this virus can cause. Here, we report a case of symmetric peripheral gangrene following H1N1 infection.

Gangrene of the extremities complicating diarrhoea and severe hypernatraemic dehydration occurred in 6 infants. This is a rare complication of gastroenteritis, and its association with hypernatraemia does not seem to have previously been emphasized. The increased blood viscosity resulting from serum hyperosmolarity may have been responsible for the gangrene, and studies in our patients suggeste...