After coronary artery bypass graft (CABG), mesenteric ischemia is a rare but dreadful complication with high mortality rates. Prophylactic use of intra-aortic balloon pump (IABP) is a common practice in patients with severe coronary artery disease awaiting CABG. During withdrawal of the IABP, there is a risk of dislodging atheromatous debris, thus causing peripheral and mesenteric emboli, which...

Patients with Calreticulin ( CALR) mutation positive essential thrombocythemia are often thought of as having a “low-risk” thrombotic complications. This report examines case patient CALR-mutation presenting peripheral retinal ischemia and subsequent neovascularization. had 2-year documented history maximum platelet count over 800,000 cells/µL. Fluorescein angiogram showed significant leakage i...

BACKGROUND MicroRNAs are key regulators of gene expression in response to injury, but there is limited knowledge of their role in ischemia-induced angiogenesis, such as in peripheral arterial disease. Here, we used an unbiased strategy and took advantage of different phenotypic outcomes that follow surgically induced hindlimb ischemia between inbred mouse strains to identify key microRNAs invol...

Background and Purpose—Cerebral microcirculatory changes during cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) are still controversial and uncertain. The aim of this study was to investigate the changes of cerebral microcirculation during cerebral vasospasm and to clarify the roles of microcirculatory disturbances in cerebral ischemia by measuring cerebral circulation time (C...

OBJECTIVE During several pathological processes such as cancer progression, thermal injury, wound healing and hindlimb ischemia, the mobilization of endothelial progenitor cells (EPCs) mobilization was enhanced with an increase of sympathetic nerve activity and norepinephrine (NE) secretion, yet the cellular and molecular mechanisms involved in the effects of NE on EPCs has less been investigat...

Abstract Introduction Peripheral arterial disease (PAD) is common in patients undergoing transcatheter aortic valve replacement (TAVR) and presents unique challenges for TAVR access. The impact of on limb ischemic events PAD unknown. Purpose Evaluate with without outcomes involving systemic cardiovascular events. Methods Patients were identified the TriNetX database. database provides access to...

Background: Peripheral arterial disease is a source of morbidity and mortality. Surgical vascular reconstruction is a treatment option but probability of failure and complications are important concerns. In this study, we evaluated outcome of surgical infrainguinal reconstruction and factors affecting graft patency for a period of one year. Methods: In this cohort study, 85 consecutive patie...

A 67 years old woman was referred to nuclear medicine center for myocardial perfusion imaging (MPI) for assessment of ischemic heart dieses (IHD).She had a history of atypical chest pain and dyspnea since about 10 days before admission. The MPI SPECT/CT was performed by stress/redistribution Tl-201 protocol. MPI was interpreted as relatively good coronary flow with no appreciable stress induced...

BACKGROUND AND PURPOSE Cerebral microcirculatory changes during cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) are still controversial and uncertain. The aim of this study was to investigate the changes of cerebral microcirculation during cerebral vasospasm and to clarify the roles of microcirculatory disturbances in cerebral ischemia by measuring cerebral circulation time (C...