R ecently, various studies have reported that periodontal disease adversely affects diabetes (1). The control of periodontal disease in elderly individuals has been reported to improve the control of blood glucose (2). Severe periodontal disease is associated with elevated blood lipopolysaccharide levels as a result of periodontogenic bacteria, which induce higher levels of interleukin-6 (IL-6)...

The direct link between smoking, lung diseases, cancer, cardiovascular disease and poor pregnancy outcomes, such as miscarriage and low birth weight, has been extensively studied. In the past three decades, there has also been an increasing awareness of the impact of smoking on periodontal disease. Smoking is considered the major environmental risk factor in the prevalence, extent and severity ...

BACKGROUND Persistent organic pollutants (POPs), which are endocrine disruptors that accumulate in adipose tissue, can increase the risk of periodontal disease through the disturbance of the immune system. OBJECTIVE We examined associations of background exposure to POPs with periodontal disease in the general population. DESIGN Cross-sectional associations of concentrations of serum POPs w...

Periodontitis is a local inflammatory process mediating destruction of periodontal tissues triggered by bacterial insult. However, this disease is also characterized by systemic inflammatory responses that contribute in the elevation of C-reactive protein (CRP) level. Circulating C-reactive protein levels are a marker of systemic inflammation and are associated with periodontal disease. Studies...

Influence of systemic disorders on periodontal diseases is well established. However, of growing interest is the effect of periodontal diseases on numerous systemic diseases or conditions like cardiovascular disease, cerebrovascular disease, diabetes, pre-term low birth weight babies, preeclampsia, respiratory infections and others including osteoporosis, cancer, rheumatoid arthritis, erectile ...

background and aims. recent reports suggest that some of the risk factors for periodontal disease are similar to those of certain systemic diseases, and that periodontal disease itself may be a risk factor for some systemic diseases. therefore, the present study investigated the association of markers of metabolic control and systemic inflammation in diabetics with the extent and severity of pe...

BACKGROUND Self-antigens such as heat shock protein 60 (HSP 60) have recently been implicated in the periodontal disease pathogenesis. There is scant evidence regarding HSP 60 levels in circulation and saliva following periodontal disease and its possible relation to systemic inflammation. AIM OF THE STUDY The aim was to evaluate the circulatory and salivary levels of HSP 60 in periodontal he...

Substantial evidence supports an association between periodontal disease and several systemic diseases including cardiovascular diseases, diabetes mellitus, respiratory diseases, adverse pregnancy outcomes, osteoporosis etc. Periodontal disease, a chronic inflammatory condition, is highly prevalent in adult populations around the world, and may be preventable. Estimates of prevalence vary betwe...

Although the connective tissue attachment represents the key issue in periodontal health or disease and in periodontal therapy, the assessment of alveolar bone changes renders valuable indirect evidence for periodontal stability, progression of disease, or repair mechanisms. In periodontal disease bacterial products trigger host cells to release mediators, which may imbalance the steady state b...