نتایج جستجو برای: perineural invasion
تعداد نتایج: 73616 فیلتر نتایج به سال:
Nonmelanoma skin cancers (squamous cell and basal cell carcinomas) occur at an epidemic rate in many countries with the worldwide incidence increasing. The sun-exposed head and neck are the most frequent sites for these cancers to arise and in most patients diagnosed with a cutaneous squamous cell carcinoma, local treatment is usually curative. However, a subset is diagnosed with a high-risk cu...
Objective: to evaluate the prognostic power of survival of a biomarkers panel formed by p53, VEGF, Bcl-2, Ki-67, and EGFR in subjects with sporadic colorectal adenocarcinoma subjected to radical surgical treatment. Methods: 114 post-surgical subjects with colorectal adenocarcinoma were studied and followed for 3 to 5 years at FundaçãoPio XII – Hospital de Câncer de Barretos. The study was condu...
The aim of this study was to evaluate the immunoexpression of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth and to correlate the results with demographic, survival, clinical (TNM staging) and histopathological variables (tumor grade, perineural invasion, embolization and bone invasion). Data from medical records and diagnoses of 41 patients we...
Objective. Colorectal cancer has a high prevalence worldwide, and new predictive and prognostic factors are needed for its early diagnosis, treatment, and follow-up. In this study, we have investigated the relationship between colorectal cancer and neutrophil to lymphocyte ratio (NLR), mean platelet volume (MPV), and platelet to lymphocyte ratio (PLR) values. Methods. Data from 71 patients admi...
CONTEXT AND OBJECTIVE Cancer of the uterine cervix is still very common in Brazil. It is important to evaluate factors that influence its prognosis. The aim here was to analyze the prevalence of prognostic anatomoclinical factors among patients with carcinoma of the uterine cervix undergoing radical hysterectomy. DESIGN AND SETTING Cross-sectional study on 301 patients with invasive carcinoma...
OBJECTIVES/HYPOTHESIS To analyze the impact of different types of perineural invasion (PNI) in squamous cell carcinoma (SCC) of the oral cavity on overall survival and recurrence rate, with a special focus on histologic subtypes and tumor stage. STUDY DESIGN Retrospective case-control study with clinicopathological analysis. METHODS Seventeen patients who received primary surgical treatment...
Tumor perineural dissemination is a hallmark of human pancreatic ductal adenocarcinoma (PDAC) and represents a major source of local tumor recurrence after surgery. In this study, we provide in vitro and in vivo evidence that the chemokine receptor CX3CR1 may be involved in the neurotropism of PDAC cells to local peripheral nerves. Neoplastic cells from PDAC cell lines and surgical specimens ex...
INVASION of the inside of the eye by squamous cell carcinoma originating in the limbal epithelium is sufficiently rare to warrant brief notice. Duke-Elder (1938) gives seven references to recorded cases, all in the literature of a generation or more ago. There appears to be no recent report of this condition and Reese (1951) refers briefly to its extreme rarity. Parsons (1904) states that invas...
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