Extreme-scale computing is set to provide the infrastructure for the advances and breakthroughs that will solve some of the hardest problems in science and engineering. However, resilience and energy concerns loom as two of the major challenges for machines at that scale. The number of components that will be assembled in the supercomputers plays a fundamental role in these challenges. First, a...

To reduce the energy consumption of modern processors, designers have proposed many energy-saving techniques. In many cases, these techniques are dynamically activated and deactivated. In systems that employ these techniques, to adapt to changes in application behavior, profiling can help determine how to manage the activation of techniques to improve a certain metric. In this paper, we propose...

ii I dedicate this dissertation to my parents Shahnaz and Kazem for their endless love, and unlimited supports, endurance and encouragement. iii Acknowledgements I would like to sincerely thank my advisor, Professor Judy Jin for her great guidance, innumerous support and encouragement, and for everything she has taught me throughout the period of my Ph.D. study, without which this dissertation ...

BACKGROUND The role of endogenous androgens for body composition and physical performance in women athletes is still not elucidated. AIM To examine the serum androgen profile in relation to body composition and physical performance in women Olympic athletes and to compare endocrine variables and body composition to controls. STUDY DESIGN Cross-sectional study, conducted between 2011 and 201...

The tread of a tyre consists of a profile (pattern of grooves, sipes, and blocks) mainly designed to improve wet performance and to inhibit aquaplaning by providing a conduit for water to be expelled underneath the tyre as it makes contact with the road surface. Testing different tread profile designs is time consuming, as it requires fabrication of a tyre set using the tread profile, followed ...

BACKGROUND AND PURPOSE The primary objective of this work was to describe the relationships between 10-year risk for stroke and multiple measures of cognitive performance for a large community-based sample of individuals who were free of clinical stroke and dementia at the time of risk assessment. METHODS Participants were 1011 men and 1164 women from the Framingham Offspring Study. The Frami...

Trichoderma reesei expresses a large number of enzymes involved in lignocellulose hydrolysis and the mechanism of how these enzymes work together is too complex to study by traditional methods, for example, by spiking with single enzymes and monitoring hydrolysis performance. In this study, a multivariate approach, partial least squares regression, was used to see whether it could help explain ...

The Life Style Performance Model provides a framework for knowing and understanding a person's total activity repertoire within the context of his or her human and nonhuman world. The model enables occupational therapy practitioners to gain a holistic perspective, thus ensuring that interventions will have more clearly discernible relevance to individual needs, interests, capacities, and self-o...

Condenser microphones of all types are traditionally made with a planar electrode parallel to an electrically conducting diaphragm, additional diaphragm stiffness at acoustic frequencies being provided by the air enclosed in a cavity behind the diaphragm. In all designs, the motion of the diaphragm in response to an acoustic signal is greatest near its center and reduces to zero at its edges. A...

Background: Cognitive impairment from cerebrovascular disease varies in scope. Methods: We studied healthy elderly individuals and those with mild cognitive impairment (MCI) or mild dementia attributed to vascular pathology, in order to assess the diagnostic utility of intra-individual variability across neuropsychological domains and the cognitive profile of vascular cognitive disorders. A lar...