Removal of the adrenal medulla in cats was performed in two stages under sodium pentobarbital anesthesia. One mg eserine per kg of body weight was in jected subcutaneously before and after medullo-adrenalectomy. Urine of 24-hour period was collected before and after injection of eserine and fluorimetrically analyzed for adrenaline and noradrenaline. The urinary excretion of adrenaline was incre...

We examined the effect of a range of pentobarbital concentrations on 0.5 mM g-aminobutyric acid (GABA)-activated channels (10 6 1 pS) in inside-out or outside-out patches from rat cultured hippocampal neurons. The conductance increased from 12 6 4 to 62 6 9 pS as the pentobarbital concentration was raised from 10 to 500 mM and the data could be fitted by a Hill-type equation. At 100 mM pentobar...

Pancreatic enzyme secretion in rats anesthesized by pentobarbital was stimulated by intravenous perfusion of the hormone pancreozymin, as indicated by a decreased amylase level in the pancreas and by specific, fine structural changes observed in an electron microscope. Rates of protein synthesis were determined by pulse labeling. Amylase, total protein, and valine were purified from pancreas an...