Sacral nerve stimulation (SNS) is an effective treatment for bladder and bowel dysfunction, and also has a role in the treatment of chronic pelvic pain. We report two cases of intractable pain associated with cauda equina syndrome (CES) that were treated successfully by SNS. The first patient suffered from intractable pelvic pain with urinary incontinence and fecal incontinence after surgery fo...

Idiopathic chronic male pelvic pain is difficult to diagnose and treat. Currently, diagnosis relies on subjective symptoms; objective measures of neuromuscular mechanisms have not been investigated. Sonographic imaging has been used to investigate these neuromuscular mechanisms in the female pelvic floor, but neither research nor books describe sonography evaluation of the male pelvic floor. Th...

Pain of sudden onset suggests an acute event, while pain that is more gradual may be seen with subacute or progressive conditions. The differential diagnosis of pain grouped by time of onset is presented in Table 16-4. The location of the pain may also be helpful, although different etiologies can lead to pain in the same region. The uterus, cervix, and adnexae share visceral innervation with t...

Objectives: The aim of this prospective study was to observe immunophenotypic patterns in patients with noninflammatory chronic pelvic pain syndrome (Cat IIIB CPPS) for further description and as possible surrogate markers for diagnosis and treatment. Methods: Eighty-eight patients with a referral diagnosis of chronic prostatitis underwent fractionated urinary cultures including expressed prost...

BACKGROUND Some patients have pelvic, pudendal, or low lumbar pain radiating into the legs that is worse while sitting but differs from pudendal neuralgia. The purpose of this study was to present a new clinical entity of neuropathic pelvic pain by pelvic neuro-vascular entrapment. OBJECTIVES To report about the locations of predilection for pelvic neurovascular entrapment. STUDY DESIGN Pro...

Low back pain during pregnancy is a common problem with a high prevalence among pregnant athletes. The etiology of pregnancy-related low back pain remains unclear, although more evidence is supporting a biomechanical/musculoskeletal origin. This article will review the causes of low back pain in athletes and pregnant women, differentiate low back from pelvic girdle pain, and discuss the treatme...

Background: Endometriosis is a chronic condition commonly presenting with pain symptoms and infertility. Endometriosis can only be diagnosed definitively at laparocopy. In view of the absence of reliable tools that can establish the diagnosis in a non-invasive way, there is a strong need for clinical prediction. Objective: To investigate the value of pain symptoms in prediction and staging of e...

its alcohol extract. In the present study, the antitumor effect of an alcohol extract was investigated using MCF7 breast cancer cells. The extract inhibited cell proliferation in a doseand time-dependent manner, which might be mediated through upregulation of p21/Waf1 and downregulation of cyclin D1. Furthermore, this compound can directly induce apoptosis in MCF-7 cells, which might be mediate...

INTRODUCTION This protocol presents the rationale and design for a trial evaluating the efficacy of intranasal oxytocin in improving pain and function among women with chronic pelvic musculoskeletal pain. Oxytocin is a neuropeptide traditionally recognised for involvement in labour, delivery and lactation. Novel evidence suggests that oxytocin decreases pain sensitivity in humans. While oxytoci...