Based on our experience and a review of the literature, we conclude that superficial, well- to moderately differentiated T1 cancers of the anal margin may be successfully treated with radiotherapy alone or local excision. Stage T2 lesions have a significant risk of inguinal lymph node metastases and should be treated with radiotherapy to the primary tumor in conjunction with elective inguinal l...

background non-melanoma skin cancers (nmsc) are the most common cancers worldwide. these cancers are not accompanied by high mortality however they lead to various complications. evaluation of nmsc predisposing factors could result in preventive measures, improvement of quality of life and reduction of medical costs. objectives this study aimed to determine predisposing factors of non-melanoma ...

background: the induction of cancer appears to be the most important effect of low-dose ionizing radiation to occur in an exposed population. in developing countries 94% of human radiation is from natural sources. in iran some high altitude regions such as, chaharmahal & bakhtiari has high levels of the natural background radiation (higher than the worldwide average). therefore, investigation o...

introduction: c - reactive protein (crp) is an acute-phase plasma protein that can be used as a marker of activation of the immune system. in response to several inflammatory reactions,the concentration of crp increases and recently have been applicated as a cancer detector in some studies. we aimed to evaluate the relation between crp level and the staging and grading of gastric and colon mali...

Robotic surgery is used for the surgical removal of female pelvic malignancies and encompasses procedures as radical cystectomy hysterectomy. The aim this paper to provide an update level 1 literature evidence about outcomes robotic compared other approaches treatment bladder, endometrial cervical cancer. A non- systematic search PubMed Scopus databases was conducted identify peer-reviewed rand...

Whole Abdomen Radiotherapy (WAR) for epithelial ovarian cancer though effective has been used sparingly due to inadequate target coverage and poor sparing of Organ At Risk (OAR) leading to significantly higher toxicities. Newer radiation techniques have shown potential for significant improvement in the therapeutic ratio. The purpose of this study was to evaluate Helical Tomotherapy(HT) for WAR...

BACKGROUND National Cancer Institute phase I #7336 and phase II #8327 clinical trials explored the safety and efficacy of triapine (NSC #663249) added to cisplatin radiochemotherapy in untreated patients with advanced-stage cervical cancer. Triapine inhibits ribonucleotide reductase, the rate-limiting enzyme responsible for DNA-building deoxyribonucleotides, and thereby, enhances radiochemosens...