In the title complex, [Pd(C(7)H(3)NO(4))(C(13)H(9)N)], the Pd(II) ion is four-coordinated in a distorted square-planar environment by one N and two O atoms from the tridentate pyridine-2,6-dicarboxyl-ate (dipic) anionic ligand and one N atom of the acridine (acr) ligand. The dipic and acr ligands are nearly planar [maximum deviation = 0.069 (3) Å in dipic and 0.091 (4) Å in acr] and the dihedra...

The title complex, [PdCl(2)(C(18)H(15)P)(2)]·0.5C(6)H(6), has the Pd(II) ion in a square-planar coordination mode (r.m.s. deviation for Pd, P and Cl atoms = 0.024 Å) with the PPh(3) and Cl ligands mutually trans. The benzene solvent mol-ecule is located about a crystallographic inversion centre. The title complex is isostructural with trans-dichloridobis(triphenyl-phosphane)-palladium(II) 1,4-d...

In the title complex, [PdBr(2)(C(7)H(8))], the Pd(II) ion lies in a distorted square-planar environment defined by the two Br atoms and the mid-points of the two π-coordinated double bonds of bicyclo-[2.2.1]hepta-2,5-diene. The complex is disposed about a crystallographic mirror plane parallel to the ac plane passing through the Pd, Br atoms and the centre of the diene ligand.

The mechanisms leading to dopaminergic neuronal loss in the substantia nigra of patients with Parkinson disease (PD) remain poorly understood. We recently reported that aberrant DNA replication mediated by DNA polymerase-β (DNA pol-β) plays a causal role in the death of postmitotic neurons in an in vitro model of PD. In the present study, we show that both proliferating cell nuclear antigen (PC...

P atients with Parkinson's disease (PD) suffer a specifi c loss of dop-aminergic neurons from the mid-brain region that controls motor function. The exact mechanism of this selective neurodegeneration is unclear, though many lines of evidence point to dysfunctional mitochondrial complex I as one root cause of the disease. Yet Choi et al. now suggest that defective regulation of micro-tubules ma...

In the centrosymmetric dinuclear title compound, [Pd2(C4H7)2(C16H14N2S2)], the metal atom is η(3)-coordinated by three C atoms of a crotyl ligand [Pd-C = 2.147 (4), 2.079 (5) and 2.098 (5) Å], the longest distance influenced by the steric inter-action with the benzyl substituents of the di-benzyl-dithio-oximidate (DTO) ligand. The Pd-N and Pd-S bonds to this ligand are 2.080 (3) and 2.3148 (9) ...

The anions of PdCl(2)L(2) and Pd(OAc)(2), precursors of palladium(0) used in cross-coupling and Heck reactions, play a crucial role in these reactions. Tricoordinated anionic complexes Pd(0)L(2)Cl(-) and Pd(0)L(2)(OAc)(-) are the effective catalysts instead of the usually postulated Pd(0)L(2) complex. The anion ligated to the palladium(0) affects the kinetics of the oxidative addition to ArI as...

Biodiesel production technology is competitive in terms of low cost and alternative source of energy which should be not only sustainable but also environmentally friendly. Designing of the lipase immobilization for biodiesel production has a remarkable impact and is still challenging. In this work, biodiesel production from soybean oil was enhanced and facilitated by using a novel biocatalyst ...

Impulse control disorders (ICDs) are relatively frequent in patients with Parkinson’s disease (PD), although it is still unclear whether an underlying pathological process plays a significant role in the development of ICD in PD apart from dopaminergic replacement therapy. In this study, we have investigated alterations of white matter tract in drug-naïve PD patients with ICDs via diffusion MRI...

The asymmetric unit of the title compound, [Pd(2)Cl(2)(C(20)H(26)P)(2)]·2CH(2)Cl(2), contains one half-mol-ecule of the palladium complex and a dichloro-methane solvent mol-ecule. In the complex, two Pd(II) atoms are bridged by two Cl atoms, with the other two coordination sites occupied by a C atom of the biphenyl system and a P atom, resulting in a distorted square-planar coordination geometr...