In the present study, we have investigated the potential neuroprotective effects of a novel peripheral benzodiazepine binding site (PBR) ligand, 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide (SSR180575), in models of central and peripheral neurodegeneration in vivo and its effect on steroid concentrations in plasma and nervous tissue. SSR180575 shows...

It is now recognized in many domains that content based image retrieval CBIR from a database of im ages cannot be carried out by using completely auto mated approaches One such domain is medical ra diology for which the clinically useful information in an image typically consists of gray level variations in highly localized regions of the image Currently it is not possible to extract these regi...

In vertebrates, variability at genes of the Major Histocompatibility Complex (MHC) represents an important adaptation for pathogen resistance, whereby high allelic diversity confers resistance to a greater number of pathogens. Pathogens can maintain diversifying selection pressure on their host's immune system that can vary in intensity based on pathogen richness, pathogen virulence, and length...

The cellular mechanisms responsible for age-related decline in the ability of Leydig cells to produce testosterone are not yet fully understood. The decline in testosterone production could result from a reduction in the Leydig cell enzymatic activities mediating testosterone synthesis, the amount of substrate available for these enzymes, or both. In the present study, we examined the effect of...

Introduction The study aimed to investigate in which way performance-based reimbursement (PBR) systems Swedish healthcare services (1) subjectively impacted physicians’ work and patient care (2) were associated with the occurrence of stress-induced exhaustion disorders among physicians. Method applied a mixed-method design. Data collected from representative sample In questionnaire, respondents...

Cultivation of Osmundea pinnatifida (Hudson) Stackhouse in flasks and/or tanks has yet to be developed beyond the lab scale. However, establishment a methodology for supply this red seaweed great potential, considering that it can exploited either as food or source biologically active compounds with potential nutraceutical, pharmaceutical and cosmetic applications. This study investigates possi...

The increasing accessibility of unmanned aerial vehicles (UAVs) drives the demand for reliable, easy-to-deploy surveillance systems to consolidate public security. This paper employs passive bistatic radar (PBR) based on a digital audio broadcast (DAB) satellite UAV monitoring in applications with power density limitations electromagnetic radiation. An advanced version extensive cancellation al...

The fundamental nature of quantum wave function has been the topic many discussions since beginning theory. It either corresponds to an element reality \((\Psi -ontic)\) or it is a subjective state knowledge about underlying -epistemic)\). Pusey, Barrett and Rudolph (PBR) have shown that epistemic interpretations are in contradiction with predictions under some assumptions. In this paper, labor...

The HLA-E locus is characterized by limited polymorphism and low levels of cell surface expression. However, the function of the products of this nonclassical MHC class I gene remains unknown. To evaluate the conservation of the MHC-E locus throughout anthropoid primate evolution, we identified the homologue of the HLA-E locus in six different New World monkey species. Full-length sequencing of...

The forest musk deer (Moschus berezovskii) is a high elevation species distributed across western China and northern Vietnam. Once abundant, habitat loss and poaching has led to a dramatic decrease in population numbers prompting the IUCN to list the species as endangered. Here, we characterized the genetic diversity of a Major Histocompatibility Complex (MHC) locus and teased apart driving fac...