Increasing interest is being shown in the link between olfaction, a complex sensory system, and cognition, particularly in the elderly. Olfaction is known to affect cognitive abilities and mood. In this article, we consider the impairment of olfactory function due to Alzheimer disease (AD), Parkinson disease (PD) and Lewy body disease (LBD), through pathological changes in the peripheral and ce...

Background: In visuo-constructional copying tasks, individuals with dementia can reproduce distorted or simplified figures resulting in the so-called ‘Constructional apraxia’ (CA) impairment. CA has been often described in Alzheimer’s disease (AD), Vascular dementia (VAD), or Fronto-temporal dementia (FTD), and less often in patients with Parkinson’s disease and associated dementia (PDD). There...

In undergoing this life, many people always try to do and get the best. New knowledge, experience, lesson, and everything that can improve the life will be done. However, many people sometimes feel confused to get those things. Feeling the limited of experience and sources to be better is one of the lacks to own. However, there is a very simple thing that can be done. This is what your teacher ...

With the aging of baby boomers, numbers Americans living with or affected by dementia will rise dramatically. By 2025, an estimated 7.2 million are expected to have Alzheimer's disease, which is most common cause dementia, accounting for 60-80% cases. 1 2021 disease facts and figures. Alzheimers Dement. 2021; 17: 327-406 Crossref PubMed Scopus (744) Google Scholar In absence medical breakthroug...

Diagnosis using a biomarker is a faster and cheaper than brain imaging. Diagnostic biomarkers are chosen based on the characteristics of the disease, specificity, sensitivity, and stability during all disease stages. For this reason, previous candidates with insoluble form in a pathophysiological stage are not useful as biomarkers for the early stage of a neurodegenerative disease. In this stud...

To help individuals with Alzheimer’s disease live at home for longer, we are developing a mobile robotic platform, called ED, intended to be used as a personal caregiver to help with the performance of activities of daily living. In a series of experiments, we study speech-based interactions between each of 10 older adults with Alzheimers disease and ED as the former makes tea in a simulated ho...