Eighty rats out of 233 developed malignant tumors in the stomach and small intestine by administration of 100 micrograms/ml N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in drinking water for 28 weeks. Fifteen lesions (30%) among the 50 small intestinal carcinomas showed ossification in the tumor, while none in the sarcomas (12 lesions) or gastric adenocarcinomas (59 lesions) showed ossification....

Large-area craniofacial defects remain a challenge for orthopaedists, hastening the need to develop facile and safe tissue engineering strategy; osteoconductive material combination of optimal growth factors microenvironment should be considered. Faced with unmet need, we propose that abundant cytokines chemokines can secreted from bone defect, provoking infiltration endogenous stem cells assis...

Dysphagia is associated with poor quality of life, and pneumonia due to aspiration life-threatening. Cervical ossification the anterior longitudinal ligament (C-OALL) one causes dysphagia, we report two cases in which dysphagia improved after surgery. Case 1: A 76-year-old man had C-OALL greater than 16 mm developed myelopathy. fall resulted upper lower limb insufficiency paralysis, posterior d...

Heterotopic ossification is a complicated and significant medical problem characterized by abnormal growth of bone in soft tissues. It occurs most commonly around a joint following surgery or trauma and is one of only a few benign conditions commonly treated with radiation therapy. In its severe form, the condition causes pain, loss of function, and restricted range of motion in the affected jo...

From 1981 to 1986 we treated 413 patients for acute spinal-cord injuries. We reviewed 356 patients followed for a minimum of two years of whom 71 (20%) developed heterotopic ossification around one or more joints. Heterotopic ossification occurred more often in male patients (23%) than in female (10%), and was most frequent in the 20to 30-year age group. It was also more common after injuries o...

Fracture of femur without evidence of severe osteoporosis rarely occurs as a result of minor external force such as a gentle passive or an active range of motion exercises. We report two cases of femoral shaft fracture occurred at the tip of heterotopic ossification of femur by a minor external force, in which the involved femur shows no evidence of remarkable osteoporosis. The possible mechani...

Epiphyseal growth plates developing during skeletal maturation are the most common temporary synchondroses in childhood. The fibrocartilaginous bridge between the superomedial pubic and the inferolateral ischial ossification center is defined as the ischiopubic synchondrosis (IPS). It is considered to be a physiologic developmental stage that can be recognized on conventional radiographs as a f...

INTRODUCTION Patellar tendon ossification is a rare pathology that may be seen as a complication after sleeve fractures of the tibial tuberosity, total patellectomy during arthroplasty, intramedullary nailing of tibial fractures, anterior cruciate ligament reconstruction with patellar tendon autograft and knee injury without fracture. However, its occurrence after partial patellectomy surgery h...

High-energy trauma patients often have multiple injuries and are frequently seen by a physiatrist following their acute care. Acetabular fractures are common in this patient population. Following surgical treatment of acetabular fractures, a very high incidence of heterotopic ossification can occur. We describe 94 patients who underwent posterior surgical fixation of an acetabular fracture. Of ...