Founder mutations, particularly 35delG in the GJB2 gene, have to a large extent contributed to the high frequency of autosomal recessive nonsyndromic hearing loss (ARNSHL). Mutations in transmembrane channel-like gene 1 (TMC1) cause ARNSHL. The p.R34X mutation is the most frequent known mutation in the TMC1 gene. To study the origin of this mutation and determine whether it arose in a common an...

Introduction and Epidemiology Neurocysticercosis (NCC) is defined as a nervous system infection by the larval stage of Taenia solium. NCC is the most common parasitic disease of the nervous system. It accounts for about 50,000 deaths per year and many times this number of people with active epilepsy (1, 2). The disease is endemic in Central and South America, sub-Saharan Africa, and in some reg...

The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...

This study analyzed the variability of rainfall and temperature in southwest coastal Bangladesh assessed impact such on local livelihood last two decades. The analysis involved use coefficient variation (CV), standardized precipitation anomaly (Z), concentration index (PCI). Linear regression was conducted to assess trends, a Mann–Kendall test performed detect significance trends. climate by us...

ABSTRACT The possibility to conduct new fieldwork projects in previously largely unexplored Iraqi Kurdistan during the past decade has reinvigorated research into transformative fifth third millennium BCE (Chalcolithic Early Bronze Age) southwest Asia when human societies grew from small, autonomous villages centralized states with urban centers. Major efforts synchronize stratigraphic sequence...

The Zang-Yi Corridor is of pivotal significance for the interactions between northwest China, southwest and mainland Southeast Asia. It has been hypothesized that formation mixed farming in this region its surrounding areas was based on multiple waves crop dispersal, with foxtail millet broomcorn arriving first from China around 5,300 cal. BP rice middle Yangtze valley after 4,700 BP. Based sys...

Computer softwares for processing Thai language are developed at National Museum of Ethnology,Osaka,Japan. We use a popular intelligent terminal TEKTRONIX 4051 for inputting and editing,IBM 370 model 138 for KWIC making and sorting, and CANON's laser beam printer for final output. Using these systems,"Kotmai Tra Sam Duang"(the Three Seals Law)which contains many kind of laws and ordinances proc...

background: despite the availability of an effective vaccine for more than three decades, hbv (hepatitis b virus) continues to infect many people worldwide, particularly in developing countries of asia. in older people at higher risk of infection, high prevalence of hbv may exist, particularly among intravenous drug users (idus). this group is among groups at higher risk of infection as they sh...

The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...