BACKGROUND Dipyrone (MET, metamizole) is a non-steroidal anti-inflammatory drug commonly used both in human and in veterinary medicine. After oral administration, is broken down rapidly to metabolites which largely retain the activity of the parent drug. Its metabolites have analgesic, antipyretic and anti-inflammatory effects. RESULTS The subjects were eight healthy male Large White post-suc...

Another patient with a congenital coagu-lation disorder due to the presence of an abnormal factor X (factor X Friuli) is presented. The proposita was a 43-yr-old white female who had a bleeding tendency from early childhood (epistaxes, monorrhagias, bleeding after tooth extractions and other surgical procedures, posttraumatic hemarthroses, bleeding from the gums and postpartum hemorrhages). The...

Impact of gestational diabetes mellitus (GDM) on the coagulation system still remains unclear and there is limited data available regarding haemostatic changes in GDM Bangladesh. This study was aimed at determining plasmaprothrombin time (PT), activated partial thromboplastin (APTT) women with GDM. cross sectional encompassed 44 (age: 28.5±3.8 years, BMI: 27.2±4.0kg/m2; mean±SD) equal number pr...

the article “oral manifestation in transplant patients” was read with enthusiasm.[1] however, the following points may be noted worthy. fissured tongue, atrophy of tongue papillae, and angular cheilitis can be observed in liver transplant patients and these may be due to concurrent hyposalivation, due to intake of diuretic drugs such as thiazides and loop diuretics.[2,3] excessive bleeding with...