BACKGROUND Small molecular CCR5 inhibitors represent a new class of drugs for treating HIV-1 infection. The evaluation of the primary resistance mutations associated with entry inhibitors during HIV-1 perinatal transmission is required because they may have a profound impact on the clinical management in MTCT. OBJECTIVES To evaluate the primary resistance mutations to maraviroc and vicriviroc...

The isolation from bud scales and partial characterisation of highly active, low molecular weight, germination inhibitors, in concentrations correlated quantitively with resistance of N52/219, N11, NCo376, and NCo293, holds promise for the development of a rapid, quantitative, chemical assay for evaluating sugarcane for pre-infectional resistance to smut. Histopathological studies on stalk and ...

in this paper, dissimilar resistance spot welding of aisi 1075 eutectoid steel to aisi 201 stainless steel is investigated experimentally. for this purpose, the experiments are designed using response surface methodology and based on four-factor, five-level central composite design. the effects of process parameters such as welding current, welding time, cooling time and electrode force are inv...

A partial diallel design was used among 20 maize inbred lines to form 110 F1 hybrids to generate information on the values of these lines for developing insect resistant maize varieties during the short rains season of 2006. The hybrids were evaluated for resistance to the C. partellus and B. fusca, and for agronomic performance over two seasons during long and short rains of 2007 at a mid-alti...