Prenatal screening tests are frequently requested for chromosomal abnormalities. Placental pathologies in early pregnancy may be overlooked, especially in partial molar pregnancy. We are reporting an incorrect preliminary diagnosed case with an increased risk of Down syndrome in her first-trimester screening test due to partial molar pregnancy.

In the United States, molar pregnancy occurs between 1 in 1,200 and 1 in 2,500 pregnancies. The critical nature of complications associated with a molar pregnancy requires advanced perioperative anesthetic management. This case report details the perioperative events of a 34-year-old gravida 5, para 3, with a partial molar pregnancy who underwent general anesthesia for a dilatation and curettag...

BACKGROUND The aim of this study was to evaluate telomerase activity in tissue from cases of gestational trophoblastic disease (GTD) and in placental tissue from early and late human pregnancies. METHODS We used a telomeric repeat amplification protocol assay to measure telomerase activity in 132 tissue samples from normal early pregnancies, spontaneous abortions, normal late pregnancies, cas...

Background: Gestational Trophoblastic Disease (GTD) is a heterogeneous group of diseases that includes partial and complete hydatidiform mole, invasive choriocarcinoma placental site trophoblastic tumour. The study aimed to determine the clinical presentation management options outcome GTD in patients admitted tertiary hospital Bangladesh.
 Materials methods: This prospective observational...

Hyperthyroidism or increased thyroid function has been reported in many patients with trophoblastic tumors, either hydatidiform mole or choriocarcinoma (1). In the US, hydatidiform mole occurs between 0.5 and 2.5 per 1000 pregnancies (2). It is more common in Asian and Latin American countries (3). Hydatidiform moles secrete large amounts of human chorionic gonadotropin (hCG), and the hCG level...

BACKGROUND Invasive mole is responsible for most cases of localized gestational trophoblastic neoplasia. Gestational trophoblastic disease describes a number of gynecologic tumors that originate in trophoblastic layer including hydatidiform mole (complete or partial), invasive mole, choriocarcinoma, placental site trophoblastic tumor and epitheloid trophoblastic tumor. Invasive mole may arise f...

OBJECTIVE To define the concentrations of inhibin in serum and tissue of patients with hydatidiform mole and assess their value as a clinical marker of the condition. DESIGN Prospective study of new patients with hydatidiform mole, comparison of paired observations, and case-control analysis. SETTING A university hospital, two large public hospitals, and a private women's clinic in Japan. ...