Enterovirus D68 (EV-D68) caused a large outbreak in the summer and fall of 2014 in the United States. It causes serious respiratory disease, but causation of associated paralysis is controversial, because the virus is not routinely identified in cerebrospinal fluid. To establish clinical correlates with human disease, we evaluated EV-D68 infection in non-lethal paralysis mouse models. Ten-day-o...

Introduction: 
 Thyrotoxic Hypokalemic Periodic Paralysis (THPP) is a rare hereditary disorder which characterized by thyroid hormone elevation, low blood potassium level and recurrent acute muscle weakness. Basic pathology thought to be the increase in activity sodium-potassium pump (Na+/K+ATPase). Case report: Here we report case of 31-year-old male that presented with weakness his legs,...

Human enterovirus D68 (EV-D68) is known to be associated with mild to severe respiratory infections. Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in respiratory samples have raised concerns about the aetiological role of this EV type in severe neurological disease. This case study is the first report of AFP following EV-D68...

Acute intermittent porphyria (AIP) is an uncommon metabolic disease that impacts multiple organs and can manifest in many ways. It often misdiagnosed due to its nonspecific symptoms. Neurovisceral signs symptoms should alert physicians consider AIP the differential after excluding more common causes. Identifying underlying cause critical preventing acute attacks, trigger avoidance optimal appro...

BACKGROUND Hyperkalaemic paralysis due to renal failure is a rare but potentially life threatening event. CASE PRESENTATION We present a patient who had sudden onset ascending flaccid paralysis. The EMS first diagnosis was acute ST-elevation myocardial infarction based on an EKG. In the emergency room (ER) due to careful history taking, serum electrolytes and repeat EKG a correct diagnosis wa...

We describe a seven-year-old girl with severe pneumonia probably associated with Mycoplasma pneumoniae who developed right-sided hemiparalysis and right central facial paralysis soon after the onset of the disease. Cerebral magnetic resonance imaging revealed left corpus striatum acute infarction and magnetic resonance angiography demonstrated left internal carotid artery occlusion. She also ha...

In 11 patients with acute Guillain-Barré polyneuropathy examined within 2 weeks of the onset of the paralysis, sensory evoked potential techniques were able to demonstrate a proximal conduction delay between Erb's point and the cervical cord in 10 subjects; while sensory conduction distal to Erb's point was much more commonly normal in the early period. Sensory evoked potential techniques provi...