The stability of the blood-aqueous barrier of the monkey eye was challenged by three different methods: anterior chamber paracentesis, intravitreal shigella endotoxin, and subconjunctival arachidonic acid. Systemic aspirin and indomethacin were ineffective in stabilizing the blood-aqueous barrier in all three of these systems.

The authors report a case where four novel strategies were successfully used in the management of advanced right ventricular failure with severe pulmonary hypertension and complex adult congenital heart disease. These included combination and optimisation of three advanced therapies for pulmonary hypertension, therapeutic abdominal paracentesis, correction of underlying metabolic/endocrine dist...

The mechanism by which ascites develops in cirrhosis is multifactorial Severe sinusoidal portal hypertension and hepatic insufficiency are the initial factors. They lead to a circulatory dysfunction characterized by arterial vasodilation, arterial hypotension, high cardiac output and hypervolemia and to renal sodium and water retention. There are evidences that arterial vasodilation in cirrhosi...