Osteosarcoma, the most common primary malignant bone tumor, usually arises in the metaphysis of long bones. Amplification and mutation of the epidermal growth factor receptor (EGFR) gene represent signature genetic abnormalities encountered in osteosarcoma. Noscapine is a benzylisoquinoline alkaloid derived from the opium poppy Papaver somniferum. Recently several studies have suggested its ant...

Isolation of a recessive aco (androcarpel organ) mutation in opium poppy Papaver somniferum, is described. The aco (aco aco) mutant plants form androcarpels in place of inner whorl stamens in their flowers. The abnormal flowers are self-fertile, as stamens in the outer whorl are normal. In aco mutant the calyx, corolla and syncarpous gynoecium are formed like in the wild type ACO plants. The an...

The opium poppy, Papaver somniferum L., is the source of both poppy seeds and opium. The commercially available seeds are widely used as ingredients for various kinds of food. IgE-mediated sensitization to poppy seeds is rare, but, if present, clinical symptoms are usually severe. Cross-sensitizations between poppy seeds and other food allergens have been described with sesame, hazelnut, rye gr...