The presence of neuritic plaques and amyloid fibrils arising from the misfolding certain proteins is principal molecular indicator neurodegenerative diseases such as Alzheimer's Parkinson's disease. Methodologies for studying early stages aggregation are rapidly to provide a better understanding mechanism fibrillization cytotoxicity identify potential targets diagnosis therapy. method presented...

Complex formation and intermolecular excited-state proton transfer (ESPT) between a dihydroxy-1,8-naphthalimide photoacid and organic bases are investigated in polar aprotic solvents. First, quantum chemical calculations are used to explore the acid-base and spectroscopic properties and to identify energetically favorable complexes. The two hydroxyl groups of the photoacid enable stepwise forma...

Lane formation dynamics of driven three-dimensional pair-ion plasmas (PIP) is investigated. Extensive Langevin simulation performed to study the influence an external electric field on behaviour PIP system. In our model, one half particles are pushed into direction by force $\boldsymbol {F}_{A}$ while other pulled opposite {F}_{B}$ . We show that if and parallel, system undergoes a non-equilibr...

The characteristic association time constant describing the formation of iron-acceptor pairs in crystalline silicon has been measured for samples of various p-type dopant concentrations and species B, Ga, and In near room temperature. The results show that the dopant species has no impact on the pairing kinetics, suggesting that the pairing process is entirely limited by iron diffusion. This co...