Immediate decreases of the concentrations of glycogen and phosphocreatine are found in continuously working muscles, and many seconds later decreases of the adenosine triphosphate are found also, The hydrolysis of the adenosine triphosphate, which involves the liberation of 2 moles of phosphate, may be detected in 40 seconds and reaches its maximumin 1 or 2 minutes in muscles working at the rat...

Kinetoplastid RNA (k-RNA) editing is a complex process in the mitochondria of kinetoplastid protozoa, including Trypanosoma brucei, that involves the guide RNA-directed insertion and deletion of uridines from precursor-mRNAs to produce mature, translatable mRNAs. k-RNA editing is performed by multiprotein complexes called editosomes. Additional non-editosome components termed k-RNA-editing acce...

23 l p23 UPDATE informs you of changes in clinical practice. This week: patient dignity l p26 PrAcTicAl ProcEDUrEs illustrates a clinical procedure. This week: removing sutures l p28 KNowlEDgE provides guided learning. This week: coPD: part one – diagnosis l p30 DEVEloPmENT highlights how nurses are developing their practice. This week: insulin regimens l p32 rEsEArcH presents the latest nursin...

Terbutaline is known to be an effective drug in the treatment of asthma which acts by P32 receptor stimulation in the lung.' If given in large doses this agent may produce side effects-such as tremor, headache, and tachycardia. Children seem to be fairly tolerant of such side effects and therefore may continue to obtain benefit at doses higher than currently recommended. The present study was u...

The production of some bacteriocins by lactic acid bacteria is regulated by induction peptides (IPs) that are secreted by a dedicated secretion system. The IP gene cbaX, for carnobacteriocin A production by Carnobacterium piscicola LV17A, and a presumptive IP gene (orf6), associated with the genetic locus for enterocin B production in Enterococcus faecium BFE 900, were fused to the signal pepti...