Lipopolysaccharide (LPS) stimulates interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF alpha) gene expression and synthesis in human peripheral blood mononuclear cells (PBMC). IL-1 can also induce PBMC to synthesize IL-1 and TNF alpha. In the present study, we used IL-1 receptor antagonist (IL-1ra) to determine the relative contribution of an IL-1-positive feedback loop to the total amou...

Introduction: Diabetes is a very common disease all over the world nowadays. Cognitive function impairment closely related with socio-demographic characteristics of diabetic patients. Objective: To assess association between sociodemographic and cognitive in adult type 2 (T2DM) Materials Methods: This cross sectional study was conducted among purposively selected 210 T2DM patients from July 201...

Background Analyzing actigraphy data using standard circadian parametric models and aggregated nonparametric indices may obscure temporal information that be a hallmark of the impairment in psychiatric disorders. Functional analysis (FDA) overcome such limitations by fully exploiting richness revealing important relationships with mental health outcomes. To our knowledge, no studies have extens...

The purpose of this study was to find efficacy values in playing microsituations in numerical equality with or without ball possession and to analyze the relation between these and the condition of winner or loser. The matches of the X World Championship of Water polo which did not end in a draw were analysed. Playing microsituations in numerical equality were evaluated by means of coefficients...

HYPOTHESIS The prediction of an intrabiliary rupture of a hepatic hydatid cyst using associated clinical factors is important for early diagnosis and proper management. DESIGN Case series of patients with hepatic hydatid cysts treated between January 1, 1992, and January 1, 2000, in a single institution. SETTING A tertiary care teaching hospital. PATIENTS The clinical findings in 116 pati...

Results: A significant association was found between the 48-hour score and the presence of pancreatic necrosis (P .001), organ failure (P=.001), and death (P .001). By contrast, the APACHE II score at admission was significantly associated only with the presence of organ failure (P=.007). Deteriorating APACHE II scores over 48 hours were significantly associated with a fatal outcome (P=.03). Th...

INTRODUCTION We evaluated relations between interleukins (IL) IL-6 and IL-10 and euthyroid sick syndrome (ESS) in patients with nonthyroidal illness (NTI). MATERIALS AND METHODS Sixty patients and 20 healthy volunteers were recruited. The patients had either chronic kidney disease (CKD), congestive heart failure (CHF), or acute myocardial infarction (MI), distributed equally in 3 subgroups. S...

OBJECTIVE Current indices of diet quality generally include intakes of specific foods or nutrients. We sought to develop an index that discriminates healthy and unhealthy eating choices for use in large surveys as a short questionnaire and as a measure in existing studies with adequate dietary data. DESIGN The Eating Choices Index (ECI) score included four components: (i) consumption of break...

Alcohol abuse is an important public health problem. In Portugal with a population of 10 millions of inhabitants, there are around 10% of alcoholics or excessive alcohol drinkers and 1% of chronically infected patients with hepatitis B virus (HBV). To examine the characteristics of patients with higher levels of alcohol consumption and to investigate the association between alcohol consumption ...

Results: Crude analysis revealed a higher mortality for uninsured patients (odds ratio [OR], 1.39; 95% confidence interval [CI], 1.36-1.42; P .001). Controlling for sex, race, age, Injury Severity Score, Revised Trauma Score, and injury mechanism (adjusted for clustering on hospital), uninsured patients had the highest mortality (OR, 1.80; 95% CI, 1.61-2.02; P .001). Subgroup analysis of young ...