We investigated the existence of the transgenerational memory of iron (Fe) deficiency stress, in Arabidopsis thaliana. Plants were grown under Fe deficiency/sufficiency, and so were their offspring. The frequency of somatic homologous recombination (SHR) events, of DNA strand breaks as well as the expression of the transcription elongation factor TFIIS-like gene increase when plants are grown u...

Malignant melanoma is characterized by rapid deterioration, early metastasis and high mortality. Cdk5 regulatory subunit-associated protein 1 (CDK5RAP1), which catalyzes 2-methylthio (ms2) modification of mitochondrial transfer RNAs, has been reported to induce cancer cell apoptosis, by a phospho-c-Jun N-terminal kinase (p-JNK) signaling pathway. The present study was the first to report on the...

Forming gas annealing causes changes in the remanent polarization (Pr), coercive field (Ec), and leakage current ~I! in both PZT @Pb~Zr,Ti!O3# and SBT (SrBi2Ta2O9) samples with a variety of top electrode materials ~Pt, Au, Ag, Cu, Ni, and In2O3!, and the degree of degradation depends strongly on the top electrode material. These results may be explained by a model that is based on the catalytic...

The idea of magnetic monopoles in spin ice has enjoyed much success at intermediate temperatures, but at low temperatures a description in terms of monopole dynamics alone is insufficient. Recently, numerical simulations were used to argue that magnetic impurities account for this discrepancy by introducing a magnetic equivalent of residual resistance in the system. Here we propose that oxygen ...

NADPH oxidase is a multisubunit complex that assembles during phagocytosis to generate reactive oxygen species. Several components of this complex have been implicated in chronic granulomatous disease and Crohn's disease, highlighting the importance of reactive oxygen species in regulating host immune response. In this study, we use genetically deficient mice to elucidate how p40(phox), one sub...

The immune system is the set of cells and organs that intervene in body's defense against certain antigens, foreign to body. This includes both elements with rapid action thus belonging non-specific immunity, also, provide a slower response, but, high specificity each antigen. Nonspecific immunity sums up cellular humoral elements, which react quickly on substances microorganisms. On other hand...

In the encapsulated environment of biohybrid artificial organs, cells often encounter a deficiency in oxygen, which lead to apoptosis, necrosis, and lost of productivity. Two vectors with constitutive CMV promoters were constructed to examine the ability of Bcl-2Delta to help C2C12 mouse myoblasts maintain exogenous protein production under hypoxia. Two additional vectors with hypoxia-inducible...

Iodine Deficiency Disorders (IDD) is a major public health problem in several areas of the world, especially developing countries. deficiency can cause goitre, cretinism, decrease intelligence, mental retardation, brain damage, deaf-mutism, and miscarriage pregnant women stillbirth as well. The purpose this research was to determine stability iodine content kinetics reaction rate fortified rice...

Saccharomyces cerevisiae is a facultative anaerobe devoid of mitochondrial alternative oxidase. In this yeast, the structure and biogenesis of the respiratory chain, on the one hand, and the functional interactions of oxidative phosphorylation with the cellular energetic metabolism, on the other, are well documented. However, to our knowledge, the molecular aspects and the physiological roles o...