BACKGROUND Urinary incontinence in women is a common problem that adversely affects quality of life. PURPOSE To synthesize evidence of management of urinary incontinence in women. DATA SOURCES MEDLINE, CINAHL, and the Cochrane Library. STUDY SELECTION 96 randomized, controlled trials (RCTs) and 3 systematic reviews published in English from 1990 through May 2007. DATA EXTRACTION Using s...

BACKGROUND The ideal measures to prevent postoperative catheter-related bladder discomfort (CRBD) remain unestablished. We conducted the systematic review and meta-analysis to clarify the significance of potential interventions. METHODS We followed the Preferred Reporting Items for Systematic review and Meta-Analysis statement guidelines, and searched databases from MEDLINE, EMBASE, and refer...

BACKGROUND Pharmacotherapy constitutes an important adjunct to behavioral therapy for the treatment of overactive bladder (OAB). Tolterodine and oxybutynin are commonly prescribed drugs for OAB treatment that exert their beneficial effect by suppressing bladder muscle contractions. However, high discontinuation rates have been observed for these drugs in clinical trials, as well as in real-worl...

Overactive bladder is a dreadful syndrome that affects a considerable number of patients. Antimuscarinics are the mainstay of pharmacotherapy for this condition. Transdermal (TD) oxybutynin (OXY) bypasses the first-pass metabolism and reduces the formation of N-desethyloxybutynin, a compound believed to be associated with anticholinergic side effects. The 3.9 mg matrix TD system is applied twic...