نتایج جستجو برای: outer membrane proteins omp

تعداد نتایج: 884310  

Journal: :Journal of bacteriology 1995
P de Wergifosse P Lintermans J N Limet A Cloeckaert

The cloning and sequencing of the Brucella abortus major 25-kDa outer membrane protein (OMP) is reported. The 25-kDa (group 3) OMP has been proposed, on the basis of amino acid composition, to be the counterpart of OmpA (D. R. Verstraete, M. T. Creasy, N. T. Caveney, C. L. Baldwin, M. W. Blab, and A. J. Winter, Infect. Immun. 35:979-989, 1982). However, the amino acid sequence predicted from th...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Troy A Walton Cristina M Sandoval C Andrew Fowler Arthur Pardi Marcelo C Sousa

Outer membrane proteins (OMPs) of gram-negative bacteria are synthesized in the cytosol and must cross the periplasm before insertion into the outer membrane. The 17-kDa protein (Skp) is a periplasmic chaperone that assists the folding and insertion of many OMPs, including OmpA, a model OMP with a membrane embedded beta-barrel domain and a periplasmic alphabeta domain. Structurally, Skp belongs...

Mannheimia haemolytica is responsible for considerable economic losses to cattle, sheep, and goat industries in many parts of the world. This bacterium isone of the causative agents of shipping fever in cattle. Current vaccines against M. haemolytica are moderately efficacious since they do not provide complete protection against the disease. Production of a...

Journal: :Infection and immunity 1992
I M Feavers J Suker A J McKenna A B Heath M C Maiden

Molecular approaches to the rapid analysis of the serotyping antigens of Neisseria meningitidis, the class 2 and 3 outer membrane proteins (OMPs), were developed, evaluated, and used to study 12 antigenic variants of these proteins. A primer set for the polymerase chain reaction (PCR) amplification of the genes encoding these antigens was devised. Low-stringency amplification of meningococcal c...

Journal: :Iranian journal of veterinary research 2016
F Mukherjee A Prasad V S Bahekar S K Rana L Rajendra G K Sharma V A Srinivasan

The use of liposome as an adjuvant and a vaccine carrier has been cited previously in the literature. It has also been shown to be effective in enhancing the immunogenicity of vaccine candidates. BALB/c mice immunized subcutaneously with outer membrane protein (OMP) of Brucella abortus S19 vaccine strain entrapped in a commercial cationic liposome (S19-OMP-liposome) for vaccine delivery, showed...

Journal: :Croatian medical journal 2009
Tajana Filipec Kanizaj Miroslava Katicić Vladimir Presecki Slavko Gasparov Vesna Colić Cvrlje Branko Kolarić Anna Mrzljak

AIM To investigate the association of gastric histological and endoscopic findings in patients with Helicobacter pylori (H. pylori), according to presence of seropositivity to 12 bacterial virulence antigens. METHODS This is a cross-sectional single-center study of 360 consecutive outpatients referred in the period of one year to upper gastrointestinal endoscopy because of dyspeptic complaint...

Journal: :The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2013
Abeer Ahmed Rushdy Mona Ibrahim Mabrouk Ferialla Abdel-Hamid Abu-Sef Zeinab Hassan Kheiralla Said Mohamed Abdel-All Neveen Mohamed Saleh

OBJECTIVES To study the potential factors include gene mutation, efflux pump and alteration of permeability associated with quinolone-resistance of Salmonella enterica strains isolated from patients with acute gastroenteritis and to evaluate the degree of synergistic activity of efflux pump inhibitors when combined with ciprofloxacin against resistant isolates. METHODS Antimicrobial resistanc...

Journal: :Structure 2009
Jungsan Sohn Robert A Grant Robert T Sauer

In the E. coli periplasm, C-terminal peptides of misfolded outer-membrane porins (OMPs) bind to the PDZ domains of the trimeric DegS protease, triggering cleavage of a transmembrane regulator and transcriptional activation of stress genes. We show that an active-site DegS mutation partially bypasses the requirement for peptide activation and acts synergistically with mutations that disrupt cont...

Journal: :Journal of oral science 2003
Yoshiaki Tsurumi Mitsuo Hayakawa Yasuko Shibata Yoshimitsu Abiko

Porphyromonas gingivalis has been implicated as a major pathogen in periodontal diseases. We previously cloned a 40-kDa outer membrane protein (OMP) gene from P. gingivalis 381 and succeeded in producing sufficient quantities of the recombinant protein for experimental use. Since antibodies against the recombinant (r) 40-kDa OMP have potent ability to kill P. gingivalis cells by complement acti...

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