Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns. Because the testis and kidney develop from the same embryonic tissue, we reasoned that OTA also may cause adducts transplacentally in the testis. We tested the hypothesis that acute ex...

Ochratoxin A (OTA) is a natural contaminant that has displayed nephrotoxicity and hepatotoxicity in mammals. It contaminates a great variety of foodstuffs and threatens people's lives. The molecular mechanism of OTA-induced toxicity has been studied since 1965. Moreover, epigenetic mechanisms are also studied in OTA-induced toxicity. Additionally, the mode of OTA epigenetic research has been ad...

The article discusses the design method of operational trans-conductance amplifier-C(OTA-C) filter based on the prototype of LC filter. It gives the OTA circuit used in the filter. And it makes a detailed analysis on characteristics of OTA. A third order OTA-C filter is presented. Its cut-off frequencies can be tuned by the bias DC current of OTA. The filter is easy to integrate. The proposed O...

Background: Ochratoxin A (OTA) and Aflatoxin B1 (AFB1) are toxic secondary  metabolites produced by certain mold species. In this primarily survey, we examined the OTA and AFB1 contamination of pearl millet grains distributed in Tunisia. Methods: Twenty-five pearl millet (Pennisetum glaucum L.) samples from different regions of Tunisia were analyzed by High Performance Liquid Chromatography co...

The current study presents a rare case of intradermal melanocytic nevus with lymphatic nevus cell embolus. A 26-year-old male presented with a slowly enlarging, pigmented nodule on the back, measuring 1 cm in diameter. Histological observations of the lesion were typical of an intradermal melanocytic nevus. The most notable feature of this nevus, however, was an aggregate of nevus cells within ...

in this paper, a low voltage and low power (lv/lp) operational transconductance amplifier (ota) using fgmos (floating-gate mos) transistor is proposed. the relative tuning range of 50 is achieved in this ota while only consumes 40 µw with 1.0 v supply voltage in tsmc 0.18 µm cmos technology. the simulation results of the proposed ota show an open loop gain of 30.2 db and a unity gain frequency ...

A malignant transformation is known to occur in many nevi such as a sebaceous nevus or a basal cell nevus, but a verrucous epidermal nevus has only rarely been associated with neoplastic changes. Keratoacanthoma, multifocal papillary apocrine adenoma, multiple malignant eccrine poroma, basal cell carcinoma and cutaneous squamous cell carcinoma (CSCC) have all been reported to develop from a ver...

Blue nevus is a benign melanocytic lesion whose most frequent variants are dendritic (common) blue nevus and cellular blue nevus. Atypical cellular blue nevus presents an intermediate histopathology between the typical and a rare variant of malignant blue nevus/melanoma arising in a cellular blue nevus. An 8-year-old child presented a pigmented lesion in the buttock since birth, but with progre...