BACKGROUND Characteristically, osteonecrosis affects younger patients who typically refer to the orthopedic surgeon for the first time in the third to fifth decades of life, in the late stages of the disease. Femoral metal-on-metal hip resurfacing is as an alternative to conventional total hip arthroplasty in treating osteoarthritis of the hip. Since there are already many reports regarding the...

Accumulating evidence has indicated that erythropoietin (EPO) plays a role in anti-apoptosis and tissue protection in a number of human diseases. The present study was implemented to evaluate these anti-apoptotic and tissue-protective effects in glucocorticoid-induced osteonecrosis in rats. Osteonecrosis was induced by low-dose lipopolysaccharide and subsequent high-dose methylprednisolone puls...

Femoral osteotomy is performed for osteonecrosis of the femoral head to prevent progression collapse and promote repair process by transposing necrotic lesion nonweight-bearing portion. The purpose this review article was summarize current knowledge on two types osteotomy: transtrochanteric anterior or posterior rotational curved varus osteotomy, both which are currently osteonecrosis, mainly i...

Case: A 58-year-old male was reviewed for bilateral hip pain 3 years post cardiac transplant, complicated by episodes of acute rejection, steroid induced diabetes, and cytomegalovirus hepatitis. He diagnosed with femoral head osteonecrosis subchondral collapse underwent staged cementless total arthroplasties. re-presented progressive right knee pain. Investigations revealed diaphyseal a rare in...

BACKGROUND Hypercoaguable state has been indicated as a major risk factor in predisposing the idiopathic osteonecrosis of the hip. Furthermore, many studies have demonstrated that low molecular weight heparin (LMWH) can reverse the pathophysiology of the osteonecrosis of the hip in thrombophilic patients. OBJECTIVE Determine whether LMWH can prevent the progression of idiopathic osteonecrosis...

The aim of this paper is to describe our surgical procedure for the treatment of osteonecrosis of the femoral head using a minimally invasive technique. We have limited the use of this procedure for patients with pre-collapse osteonecrosis of the femoral head (Ficat Stage I or II). To treat osteonecrosis of the femoral head at our institution we currently use a combination of outpatient, minima...

BACKGROUND Multiple osteonecrotic foci can be clinically silent when located in metaphyses and becomes painful when it affects juxta-articular areas. The purpose of this study was to assess the value of fast MR imaging to depict the underlying pathology in cases with skeletal pain other than the already diagnosed hip osteonecrosis. METHODS/DESIGN Between 2008 and 2013, 49 patients with alread...

BACKGROUND Bisphosphonates are drugs used in the treatment of lytic bone metastases, multiple myeloma, hypercalcemia of malignant origin, osteoporosis, and diseases such as Paget's disease. Recently osteonecrosis of the jaw has been associated with the use of bisphosphonates. This study describes the imaging findings of bisphosphonate-associated osteonecrosis of the jaws. PATIENTS AND METHODS...

Bisphosphonates are potent and effective drugs frequently used to prevent the skeletal complications associated with postmenopausal osteoporosis in women, to manage patients with multiple myeloma, hypercalcemia, and metastasis of cancer to the bone. The search for new medications with the same therapeutic effectiveness as the bisphosphonates but fewer side effects has resulted in the discovery ...

This paper discusses extensions to the language Ei el, required to write more comprehensive software speci cations, where a speci cation in Ei el is a collection of class interfaces with features speci ed using an assertion language (i.e. a BON static model). The focus of the paper is the extension of the assertion language with quanti cation. Two forms of quanti cation are identi ed, which are...