BACKGROUND Inconsistent reports are available in the literature regarding the oxidative status and antioxidant capacity during the pathogenesis of gestational diabetes. Present study was aimed to evaluate oxidative stress during the development of gestational diabetes and to evaluate antioxidant capability in non-pregnant (control), pregnant and gestational diabetics. METHODS The study consis...

Effect of mercury on blood and its components of fish Labeo rohita was carried out in this study. The LC50 dose of 57.074 mg/L and mercuric chloride exposure for 96 h resulted in significant changes in the physico-chemical properties such as hemoglobin, osmotic fragility and blood cell counts. Further, mercury exposure also caused a considerable reduction in the sulf-hydryl group of glutathione...

In vitro treatment of erythrocytes of normal and hypercholesterolemic rats with N-nitrosodiethylamine (NDEA), an important carcinogen frequently present in human environment and food chain resulted in a marginal increase in osmotic fragility of erythrocytes without affecting their antioxygenic potential as evidenced by insignificant effect on lipid peroxidation (LPO). However, (LPO) of all the ...

An osmotically fragile L-form of Streptococcus pyogenes, type 12, was quickly rendered osmotically stable by decreasing the sodium chloride content of the growth medium and with the temporary use of oleic acid. The change from osmotic fragility to stability was accompanied by changes in cell yield, generation time, saturated/unsaturated fatty acid ratio of the membrane, and cytoplasmic protein ...

In vitro antioxidant and erythrocyte protecting activities by aqueous extract of Ficus thonningii leaves on blood cells were studied in acetaminophen treated rats. The extract was safe at limit dose of 5000 mg kg-1body weight. The extract demonstrated dose dependent antihemolytic effect at dose levels between 50 and 200 m...

By GEORGE M. GUEST, M.D. V ARIOUS investigators have postulated two main principles which seem to govern the swelling and hemolysis of red blood cells suspended in hypotonic salt solutions: namely, the cells imbibe water according to the laws of osmosis, and their maximum swelling is limited by an inelastic surface membrane. According to this concept, hemolysis occurs when the erythrocytes in h...