The most ideal implant models in the dental and orthopedic fields to minimize the failure rate of implantation involve the improvement of osseointegration with host bone. Therefore, a focus of this study is the preparation of surface-modified titanium (Ti) samples of disc and screw types using dexamethasone (DEX) and/or growth and differentiation factor-5 (GDF-5), as well as the evaluation of t...

The idea of using composite in bone implant came since 1980 . Considering the observed problems and failures from the previous materials, using composite materials with higher strength and stiffness and more similarity to natural bone had started to develop. In medical composites at least one of the constituent materials should be bioactive (metal-polymer or ceramic). The name of composites is ...

Treating large bone defects is still a clinical challenge without perfect solution, mainly due to the unavailability of suitable implants. Additively manufactured (AM) absorbable porous metals provide unparalleled opportunities realize challenging requirements for bone-mimetic Firstly, multi-scale geometries such implants can be customized mimic micro-architecture and mechanical properties huma...

The process of bone healing requires the restoration of both anatomy and physiology, and there is a recognized need for innovative biomaterials that facilitate remodeling throughout this complex process. While porous scaffolds with a high degree of interconnectivity are known to accelerate cellular infiltration and new bone formation, the presence of pores significantly diminishes the initial m...

Background and Aim: Implant site preparation with minimal trauma is an important factor in success of implant treatment and has a great effect on osseointegration. Piezoelectric bone surgery was introduced as a modern technique for micrometric osteotomy with precise, controllable action. Preservation of osteoblast cell viability is critical to achieve successful osseointegration. The present st...

The main criterion for assessing the engraftment of dental implants is their high-quality osseointegration [1]. Unreasonable loads exerted on a implant integrated into bone tissue lead to its premature rejection. Adequate also influenced by shape, size, quality installation, adherence operating protocol, as well start date subsequent prosthetics [2]. A qualitative method determining stability a...

The objective of our work is to improve the osseointegration of titanium (and its alloys) used in dental and orthopedic applications. To do this, we have been coating these metals with glasses whose compositions are based upon Bioglass®, which is a bioactive glass developed by Hench et al. Bioactive glasses have the property of forming an apatite layer (and therefore can chemically bond to bone...

Ideal implant-cement or implant-bone interfaces are required for implant fixation and the filling of tissue defects created by disease. Micron- to nanosize osseointegrated features, such as surface roughness, fibers, porosity, and particles, have been fused with implants for improving the osseointegration of an implant with the host tissue in orthopedics and dentistry. The effects of fibers and...