An efficient Pd-catalyzed decarboxylative ortho-arylation of amides with aryl acylperoxides was developed. A variety of anilides reacted with aryl acylperoxides to afford the corresponding ortho-arylation products, and N-methoxyarylamides generated phenanthridinones.

Tetraiodo-ortho-carborane based X-ray contrast agents can be readily prepared in a high yield, fast, clean, regioselective fashion by a solvent-free reaction of ortho-carboranes with iodine in sealed tubes.

An enantioselective hydroxylative dearomatization of 2-naphthols with oxaziridines has been accomplished using a N,N'-dioxide-scandium(iii) complex catalyst. Various substituted ortho-quinols could be obtained in high yields (up to 99%) and enantioselectivities (up to 95 : 5 er). This methodology could be applied in the synthesis of bioactive lacinilenes in a gram-scale reaction. Based on the e...

A Rh(III)-catalyzed oxidative [4 + 1] cycloaddition of benzohydroxamic acids and α-diazoesters is achieved to afford benzolactams in up to 93% yields. With the N-OAc amido moiety as a directing group, the ortho-C-H is selectively functionalized and the catalytic reaction exhibits excellent tolerance to different functional substituents. A notable rhodacyclic complex is isolated and structurally...

The mol-ecule of the title complex, [Cu(C(6)H(2)N(3)O(7))(2)(C(3)H(7)NO)(2)], is disposed about a crystallographic centre of symmetry. The Cu(II) cation is six-coordinated by two phenolate O atoms and two ortho-nitro O atoms of two picrate units and by two carbonyl O atoms from two coordinated dimethyl-formamide mol-ecules, forming a distorted octa-hedral geometry.

The monoclinic title complex, [PtI(2)(C(8)H(12))], characterized by a twisted cyclo-octa-diene ring, is similar to its Cl and Br ortho-rhom-bic homologues. The observed Pt-I bond distances of 2.6094 (5) and 2.6130 (5) Å are in the expected range for PtI(2) complexes. The C=C double bonds in the mol-ecule differ significantly [1.373 (10) and 1.403 (10) Å]. As expected for a platinum(II) complex,...

Rovibrational spectroscopy of molecules boasts extremely high precision, but its usefulness relies on the assignment of spectral features to corresponding quantum mechanical transitions. In the case of ortho-H(2)-CO, a weakly bound complex abundant in the interstellar medium (although not yet observed there), the rather complex spectrum has been unexplained for more than a decade. We assigned t...

A chiral phosphine auxiliary was generated with excellent ee via catalytic asymmetric hydrophosphination of 3-(naphthalen-1-ylmethylene)pentane-2,4-dione. The subsequent metal complexation of the monophosphine yielded two different coordination complexes depending on the reaction conditions. The ortho-palladation of both coordination complexes resulted in the formation of a single dimeric phosp...

BACKGROUND Primary Hypertension (HT) is the most prevalent cardiovascular disorder worldwide and is accompanied by significant morbidity and mortality. OBJECTIVES The present study aimed to investigate the kinetics of orthostatic Blood Pressure (BP) in primary hypertensive patients during the change from supine position to standing position as well as during the standing position using the Or...