نتایج جستجو برای: orotic acid

تعداد نتایج: 747474  

Journal: :Physiological genomics 2004
Julian L Griffin Stephanie A Bonney Chris Mann Abdul M Hebbachi Geoff F Gibbons Jeremy K Nicholson Carol C Shoulders James Scott

In functional genomics, DNA microarrays for gene expression profiling are increasingly being used to provide insights into biological function or pathology. To better understand the significance of the multiple transcriptional changes across a time period, the temporal changes in phenotype must be described. Orotic acid-induced fatty liver disease was investigated at the transcriptional and met...

Journal: :Journal of Biological Chemistry 1952

Journal: :Journal of Biological Chemistry 1949

Journal: :The Journal of clinical investigation 1977
A Cohen G E Staal A J Ammann D W Martin

The urines of two unrelated children with inherited deficiencies of purine nucleoside phosphorylase have been found to contain significant quantities of orotic acid in addition to the previously reported purine nucleosides. The data are consistent with some cell types of these immunodeficient patients being deplete of pyrophosphoribosylphosphate, a precursor of both purine, and pyrimidine nucle...

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