A variety of antioxidant compounds derived from natural products (nutraceuticals) have demonstrated neuroprotective activity in either in vitro or in vivo models of neuronal cell death or neurodegeneration, respectively. These natural antioxidants fall into several distinct groups based on their chemical structures: (1) flavonoid polyphenols like epigallocatechin 3-gallate (EGCG) from green tea...

Diallyl sulfide (DAS) and diallyl disulfide (DADS), two garlic constituents, were found previously to inhibit aflatoxin B(1) (AFB(1))-initiated carcinogenesis in rat liver, DADS being the most effective. In order to study the mechanisms involved in this protection, we have examined the ability of liver microsomes and cytosols from DAS- and DADS-treated rats to modulate the mutagenicity and the ...

Abstract. Organosulfur compounds (OrgSs), especially organosulfates, have been widely reported to be present in large quantities particulate organic matter found various atmospheric environments. Despite hundreds of organosulfates and their formation mechanisms being previously identified, a fraction OrgSs remain unexplained at the molecular level, better understanding pathways critical environ...

The medicinal use of garlic dates back thousands of years, but there was little scientific support of its therapeutic and pharmacologic properties until recently. In the past decade, the cancer-protective effects of garlic have been well established by epidemiologic studies and animal experiments. However, the cardiovascular-protective properties of garlic are less well understood. In particula...

The properties of garlic (Allium sativum L.) are attributed to organosulfur compounds. Although these compounds change during cultivation and storage, there is no report of their simultaneous analysis. Here, a newly developed analytical method with a rapid and simple sample preparation to determine four sulfoxides and three gamma-glutamyl peptides in garlic is reported. All garlic samples were ...

The first remarkable property associated to metallophthalocyanines (MPcs) was their chemical “inertness”, which made and make them very attractive as stable durable industrial dyes. Nevertheless, rich redox chemistry also explored in the last decades, making available a solid detailed knowledge background for further studies on suitability of MPcs catalysts. An overlook catalytic activity with ...

Onion is one of the civilization’s oldest medicines and is described as the dynamite of natural foods. In the current day scenario, herbal medicines have gained global significance with both medicinal and cost-effective implications. Thus, scientific appraisal has turned out to be a prerequisite for recognition of physical fitness in nature. An exceptionally strong antioxidant, onion is the ric...