Orally dispersive tablets are solid dosage forms that dissolve in the mouth within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due its fast breakdown, which also causes effects start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young undevelop...

The purpose of this research was to mask the intensely bitter taste of diclofenac sodium and to formulate an orally-disintegrating tablet (ODT)) of the taste-masked drug. The methods commonly employed for achieving effective taste masking include various physical and chemical methods that prevent the drug substance from interaction with the taste buds. In this present study we have used veegum(...

Fast-dissolving drug-delivery systems were first developed in the late 1970s as an alternative to tablets, capsules, and syrups for the patients of pediatric and geriatric who faces difficulties in swallowing conventional oral solid dosage forms. On the basis of this need, a variety of orally disintegrating tablet (ODT) formats were commercialized. Most ODT products were formulated to disintegr...

The 'Zomig Appropriate for Primary care' programme was developed to address the needs of primary care physicians (PCPs) to improve migraine management. As part of the programme, an international, open-label, 6-month clinical study was performed. The study included new and tangible outcome variables relevant to PCPs and recruited patients presenting in primary care with an established migraine d...

A multivariate statistical technique was applied to the design of an orally disintegrating tablet and to clarify the causal correlation among variables of the manufacturing process and pharmaceutical responses. Orally disintegrating tablets (ODTs) composed mainly of mannitol were prepared via the wet-granulation method using crystal transition from the δ to the β form of mannitol. Process param...

The aim and objective of orally disintegrating tablets by direct compression method was emerged from desired to provide patient with a conventional mean of taking their medication. Difficulty in swallowing (Dysphagia) is a common problem of all age groups, especially elderly and pediatrics, because of physiological changes associated with these groups of patients. In the present work Ondansetro...

The aim of this study was to prepare, using taste masked granules, rapidly disintegrating tablets of chlorpheniramine maleate, a bitter drug. The taste masked granules were prepared using aminoalkyl methacrylate copolymers (Eudragit E-100) by the extrusion method. In vitro release profile obtained at pH 6.8 indicate that perceivable amount of drug will not be released in saliva while high perce...